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PHM 701 > Schizophrenia > Flashcards

Schizophrenia Flashcards

1
Q

1st gen Antipsychotics

A

Chlorpromazine
Fluphenazine
Haloperidol
Perphenazine
Thioridazine
Thiothixene

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2
Q

What 1st gen Antipsychotics are available as Long Acting Injectables?

A

Fluphenazine
Haloperidol

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3
Q

1st gen Antipsychotics ADEs

A

EPS
QTc Prolongation
Prolactin Elevation
Dermatologic
Photo-sensitivity
Blue-gray skin
Orhtostatic hypotension
Altered thermoregulation

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4
Q

2nd gen Antipsychotics

A

Aripiprazole
Asenapine
Brexipiprazole
Cariprazine
Clozapine
Iloperidone
Lumateperone
Lurasidone
Olanzapine
Paliperidone
Quietapine
Risperidone
Ziprasidone

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5
Q

What 2nd gen Antipsychotics are used to treat MDD?

A

Aripiprazole
Brexipiprazole
Olanzapine (w/ fluoxetine)
Risperidone

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6
Q

Which 2nd gen Antipsychotics are available as long acting injectable?

A

Aripiprazole
Olanzapine
Paliperidone
Risperidone

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7
Q

2nd gen Antipsychotics ADEs

A

Metabolic syndrome
Qtc Prolongation
Blood dyscrasias/neutropenias
Seizure thresholds
Anticholinergic effects
Sedation
Prolactin Elevation
Ophthalmic effects

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8
Q

Which antipsychotics are FDA-approved for use in pediatrics

A

Aripiprazole
Lurasidone
Olanzapine
Paliperidone
Quietapine
Risperidone

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9
Q

Which Antipsychotic comes with NIOSH guidelines?

A

Ziprasidone

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10
Q

What is the BBW associated with antipsychotics?

A

Dementia - related psychosis

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11
Q

Which 1st gen Antipsychotics require a PO overlap?

A

Fluphenazine
Haloperidol

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12
Q

Which 2nd gen Antipsycotics require a PO overlap?

A

Aripiprazole
Risperidone

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13
Q

Describe Acute Dystonia

A

Long painful contractions
Stiffnes

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14
Q

Treatment for Acute Dystonia

A

Anticholinergics
IM BZDs

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15
Q

Describe Pseudo-Parkinsonism

A

Bradykinesia

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16
Q

Treatment for Pseudo-Parkinsonism

A

Anticholinergics

17
Q

Describe Akathasia

A

Restlessness
Pacing around

18
Q

Treatment for Akathasia

A

Beta blockers

19
Q

Describe Tardive Dyskinesia

A

Tongue thrusting
lip biting
Chewing

20
Q

Treatment for Tardive Dyskinesia

A

Prevention

21
Q

What medication should you not use in Tardive Dyskinesia

A

Anticholinergics as they mask the symptoms of tardive Dyskinesia

22
Q

Beta blockers used in Akathasia

A

Nadolol
Propranolol
Metoprolol

23
Q

Benzodiazepines used in EPS Treatment

A

Clonazepam
Diazepam
Lorazepam

24
Q

Medications for EPS Treatment

A

Diphenhydramine
Benztropine
Trihexyphenidyl
Amantadine
BZDs

25
Q

What drugs are used fro VMAT2 inhibition?

A

Valbenazine
Deutetrabenazine

26
Q

What is the caution with the benazines?

A

Hepatic impairment
ContraI with Deutetra

27
Q

What 2nd Gen Antipsychotics can cause EPS?

A

Risperidone
Paliperidone

28
Q

What 2nd Gen Antipsychotics cause the most weight gain?

A

Clozapine
Olanzapine
Quetiapine

29
Q

What 2nd gen Antipsychotics cause the least weight gain?

A

Aripiprazole
Lurasidone
Ziprasidone

30
Q

What 2nd gen Antipsychotics are most sedating?

A

Quetiapine
Clozapine

31
Q

What APS are high potency

A

Fluphenazine
Haloperidol

32
Q

Which APS are low potency

A

Chlorpromazine
Thioridazine

33
Q

What 1st gen APS are the most sedating?

A

Chlopromazine
Thioridazine

33
Q

Which 1st gen APS cause the most EPS?

A

Fluphenazine
Haloperidol

PHM 701 (8 decks)

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