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MuE, Mtm, Ipc > Schizophrenia > Flashcards

Schizophrenia Flashcards

1
Q

Schizophrenia is a psychiatric disorder characterized by symptoms of chronic or recurrent psychosis. What are the objectives of treating schizophrenia with any
maintenance antipsychotic therapy?

A

L

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2
Q

What treatment options will you recommend for an adult patient with schizophrenia who shows persistent residual symptoms despite initial antipsychotic treatment?

A

K

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3
Q

What treatment option will you recommend for an patient with schizophrenia who is resistant to two antipsychotic medications (failed risperidone and aripiprazole)?

A

,

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4
Q

What are the monitoring parameters for antipsychotics medications

A

K

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5
Q

What are the ‘Decanoates’? what is the rationale behind their use? what is mechanism of their extended release?

A

M

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6
Q

Optional) What is the Z-track injection technique? Why is this used when administering the FGAs LAI?

A

K

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7
Q

First generation antipsychotic
Mechanism
Positive symptoms
Negative symptoms
EPS
Prolactin
Metabolic disturbance
QTC prolongation
Neuroleptic syndrome
Cost

A

S

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8
Q

Second generation antipsychotic

Mechanism
Positive symptoms
Negative symptoms
EPS
Prolactin
Metabolic disturbance
QTC prolongation
Neuroleptic syndrome
Cost

A

D

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9
Q

For patient with refractory positive symptoms

A

D

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10
Q

High potency

A

D

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11
Q

Low potency

A

D

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12
Q

Higher rate intravenous haloperidol compared with other FGA

A

K

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13
Q

Least cost

A

K

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14
Q

Atypical antipsychotic

A

S

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15
Q

Neuroloptic

A

D

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16
Q

Conventional

A

D

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17
Q

CYP1A2

A

N

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18
Q

Max dose

A

K

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19
Q

900

A

K

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20
Q

30

A

M

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21
Q

800

A

I

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22
Q

8

A

M

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23
Q

160

A

N

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24
Q

Iv very strong sedative where as oral not that sedating

A

K

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25
Q

worst QTC prolongation

A

M

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26
Q

active metabolite of risperdone

A

K

27
Q

least metabolic disturbance

A

K

28
Q

strongest for sedation ( anti histamine )

A

K

29
Q

Contraindication in sever hepatic or renal

A

O

30
Q

Augmentation of antidepressants

A

E

31
Q

Agranulocytosis

A

D

32
Q

Need to be taken with food

A

D

33
Q

Bioavailability with oral dosing is 60% better oral and parenteral

A

S

34
Q

CYP2D6

A

E

35
Q

Myocarditis and cardiomyopathy

A

D

36
Q

Sialorrhea

A

C

37
Q

Choleststaic and jaundice

A

D

38
Q

Pigmentary

A

X

39
Q

Retinopathy

A

D

40
Q

Seziure

A

D

41
Q

Benztropine

A

D

42
Q

Diphenhydramine

A

C

43
Q

Reality distortion

A

F

44
Q

Hallucination

A
45
Q

Delusion

A

D

46
Q

Diorganized though and behavioral

A

V

47
Q

Avolition

A

F

48
Q

Anhedonia

A

C

49
Q

Poverty of speech

A

F

50
Q

Flattened effect

A

G

51
Q

Social withdrawl

A

F

52
Q

Akathisia

A

D

53
Q

Rigidty

A
54
Q

Bradykineasia

A

F

55
Q

Tremor

A

F

56
Q

Acute dystonic

A
57
Q

Aripiorazole extended release

A

D

58
Q

Aripoprazole lauroxil

A

D

59
Q

Olanzpine pamoate

A

D

60
Q

Paliperidone palmitate

A
61
Q

Risperidone microsphere

A
62
Q

Risperidone extended release subcutaneous injection

A
63
Q

Fluphenazine deconate

A
64
Q

Haloperidol decanoate

A

MuE, Mtm, Ipc (13 decks)

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