Schizophrenia Flashcards

1
Q

schizophrenia spectrum

A

a group of psychotic disorderes by severe disturbances of thought and associative looseness, impaired reality testing and limited socialization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

psychosis

A

total inability to recognize ability reality, not a diagnosis by a symptom

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

schizophreniform

A

duration of symptoms is < 6 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

schizoaffective

A

symptoms are concurrent with major depressive, manic or mixed episode

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

delusional

A

non-bizarre delusions without other symptoms of psychosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

brief psychotic

A

acute onset of symptoms lasting < 1 month

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

substance-induced psychotic

A

psychosis within one month of substance intoxication or withdrawal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

substance use and tobacco use disorders occur in how many schizo patients

A

50% of schizo patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is the leading cause of pre-mature death in schizo

A

suicide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the schizo gene

A

C-4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

dopamine hypothesis

A

+ symptoms are associated with excessive dopamine transmission

  • symptoms are associated with too little dopamine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

non-genetic prenatal complications

A

viral infections
poor nutrition
hypoxia
exposure to toxins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

psychological stressors

A

childhood sexual abuse
chronic poverty
high crime

stress increases cortisol levels which can cause other issues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

environmental stressors for schizophrenia

A

street drugs before age 21

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

DSM-5 schizo diagnosis

A

2+ of the following for 1 month:

delusions
hallucinations
disorganized speech
disorganized/catatonic behavior
negative symptoms
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

positive symptoms

A

hallucinations
delusions
disorganized speech
bizarre behavior

acute onset - respond to antipsychotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

hallucination types

A
auditory
visual
tactile
olfactory
gustatory
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

command hallucinations

A

if they hear it in a familiar voice they are more likely to do it

ask what the voices are telling them to do

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

personal boundary difficulties

A

depersonalization

derealization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

delusions

A

ideas of:

reference
persecution
grandeur
somatic
jealousy
control
thought broadcasting
thought insertion
thought withdrawal
21
Q

associative looseness

A

flight of ideas

22
Q

clanging

A

rhyming or sound alike words

23
Q

neologisms

A

made-up words

24
Q

echolalia

A

repeated words

25
Q

word salad

A

mix of meaningless words

26
Q

negative symptoms

A

affect blunt

27
Q

alogia

A

poverty of speech and content

28
Q

avolition

A

no motivatoin

29
Q

anergia

A

no energy

30
Q

anhedonia

A

no pleasure

31
Q

poverty of speech

A

answers briefly

32
Q

thought blocking

A

interruption in thoughts

33
Q

FGA antagonizes

A

DA

34
Q

FGA has a greater risk of

A

EPS

35
Q

SGA antagonizes

A

serotonin and dopamine

36
Q

SGA has a greater risk of

A

metabolic syndrome

37
Q

why is SGA harder to get

A

more costly

38
Q

black box warning for FGA

A

not approved for dementia-related psychosis

39
Q

which FGA causes QT prolongation

A

thioridazine

40
Q

common anti-psychotic X10

A
sedation
hypotension
anticholinergic
weight gain
photosensitivity
sexual dysfunction
increased prolactin levels
seizures
metabolic syndrome
EPS
41
Q

EPS

A

akathisia
pseudoparkinsonism
acute dystonia

42
Q

antiparkinson drugs X4

A

trihexyphenidyl
benztropine
dipenhydramine
biperiden

43
Q

tardive dyskinesia

A

serious and irreversible EPS side effect after prolonged treatment

symptoms may subside after meds are discontinued or may be permanent

44
Q

AIMS

A

abnormal involuntary movement scale

45
Q

metabolic syndrome

A

cluster of conditions that increase risk for heart dz, DM, stroke

46
Q

how is metabolic syndrome diagnosed

A
3+ of the following
obesity
HTN
hyperglycemia
high cholesterol
47
Q

Neuroleptic malignant syndrome

A

rare but potentially fatal SE of antipsychotic

48
Q

symptoms of NMS X9

A
decreased consciousness
muscular rigidity
increased muscle enzymes
hyperpyrexia
HTN
tachycardia
tachypnea
diaphoresis
drooling
49
Q

how to treat NMS

A

bromocriptine
dantrolene
IVF