Scenario 17 - haemolytic anaemia Flashcards
1
Q
Recall one blood marker that will be very high in haemolytic anaemia?
A
Creatinine
2
Q
What would be seen on a blood film in haemolytic anaemia?
A
Schistocytes
3
Q
Recall 4 symptoms/signs of haemolytic anaemia
A
Splenomegaly
Jaundice
Malaise
Diarrhoea
4
Q
Describe the pathophysiology of microangiopathic haemolytic anaemia (MAHA)
A
Small vessels constrict - red cells break up as they squeeze through them - small clots are formed - vicious cycle begins as vessels narrow further
5
Q
What test can be done to definitively say there is red cell breakdown?
A
D-dimer
6
Q
What is the most common cause of the haemolytic uraemic syndrome?
A
E157 Haemorrhagic E coli
7
Q
What is TTP?
A
Thrombocytic thrombocytopaenic purpura
HUS + fever + neurological manifestations
