Scenario (1) structure and function of neurone Flashcards

1
Q

cranial nerves

A

classified as peripheral nerves supply the face

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2
Q

Non-excitable cells

A

Glial cells- tumours in the brain due to damage

more numerous than neurones 10:1

  • support
  • protection
  • nutrition
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3
Q

what do schwann and oligodendrocytes cells produce

A

Myeline

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4
Q

CNS glial cells PNS glial cells

A

X4 in the CNS

  1. Astrocytes
  2. Oligodendrocytes
  3. Microglial
  4. Ependyma

X2 PNS

  1. Schwann
  2. Satilite cells
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5
Q

CNS glial cells

A

Astrocytes: ⭐️shaped- control exchange chemicals circulatory+nervous system
transfer materials between vascular systems and nueral tissue form the blood brain barrier

Oligodedrocutes: 🟣cells with few processes
synthesise and selectively myelinateneural axons

Microglial: 🟠 few processes
migratory cells that mediate immune response in CNS + PNS (phaocytic role)

Ependyma cells: epithelial cells
Line ventricles (ciliates circulation CSF)
CSF cerebral spinal fluid- protection, nutrition

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6
Q

what is within the CNS

A
  • Grey matter spread over surface= cortex
  • cell bodies grouped together= nuclei
  • a bundle of axons (whie) that travel along side eachother= tract, lemniscus,fasciculus, capsule
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7
Q

what is within the PNS

A

cell bodies grouped together= ganglion

bundles of axons= peripheral or cranial nerves

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8
Q

What is Guillain–Barré syndrome (GBS)

A

Rapid-onset muscle weakness caused by the immune system damaging the peripheral nervous system. Attacks myelin

  • some recover some don’t
  • pain
  • parasthesia- numbness

MS
Attacks myelin in CNS

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9
Q

Extrafusal muscle fibers

A

Skeletal standard muscle fibers that are innervated by alpha motor neurons and generate tension by contracting allowing for skeletal movement.

They make up large mass of skeletal (striated) muscle and are attached to bone by fibrous tissue extensions (tendons).

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10
Q

Intrafusal muscle fibers

A

Highly specialised sensory receptors

Skeletal muscle fibers that serve as specialized sensory organs (proprioceptors) that detect the amount and rate of change in length of a muscle

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11
Q

What is a motor unit

A

Combination of a single motor neurone and the muscle fibres that it innervates

The axon of an individual alpha motor neurone branches within the target muscle and innervates a number of muscle fibres

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12
Q

What does a motor neurone consist off

A

Small numbers of muscle fibres in delicate muscles eg hand for precise movements

Large numbers of muscle fibres in postural muscles eg quads

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13
Q

Nerve endings

A

Either afferent or efferent

Respond to mechanical thermo or chemical stimulation

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14
Q

What are nerve endings called that induce movements

A

Motor

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15
Q

Efferent nerve endings

A

Resemble the synapse that occur between neurones

Transmission Is chemical: depolarisation of endings causes a release of a neurotransmitter that acts on receptors in the target cell

In straited muscle both alpha motor neurones (innervate extrafusal muscle) and gamma motor neurones (innervate intrafusal muscle) end at NUROMUSCULAR JUNCTIONS or MOTOR END PLATES

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16
Q

PNS glial cells

A

Swann cells= produce single myelin

Satilite cell= support protect neurones by providing nutritients like astrocytes. Protective cushioning cells.

17
Q

How many neuroglia cells are there

A

X4 in the CNS

  1. Astrocytes
  2. Oligodendrocytes
  3. Microglial
  4. Ependyma

X2 PNS

  1. Schwann
  2. Satilite cells
18
Q

Nerve transmission speeds PNS

A

X

19
Q

Nerve conduction tests

A

NHS

20
Q

Spatial summation

A

Multiple presynaptic neurones together release enough neurotransmitter (e.g. acetylcholine) to exceed the threshold of the postsynaptic neurone.

21
Q

Temporal summation

A

Occurs when one presynaptic neurone releases neurotransmitter many times over a period of time.

Relay neurone