Scar improvement Flashcards
How long does it take for a scar to mature?
At least 2 years
After how long can an intervention be considered if scar appearance is not favorable?
Usually 60-90 days
In general, how can surgical excision orientation improve scar formation?
Placement along relaxed skin tension lines and borders of aesthetic subunits
What types of scars are amendable to massage?
Mild depressed scars, mild webbing, mild pin cushioning
How does pressure therapy help improve scars?
Thins the epidermis, decreases edema, decreases blood flow and oxygen
(loses effect after 6 months)
What is the mechanism of topical steroids improving scars?
Decreases activity of fibroblasts and decreases collagen production
What is the mechanism of imiquimod helping with scar formation?
Stimulates IFN-alpha which leads to decreased TGF-beta
-IFN-alpha also increases collagen breakdown
What can imiquimod be tried for in terms of scars?
Can be used after excision to prevent keloid (results mixed)
What is the mechanism of intralesional 5-FU for scars?
Blocks TGF-beta2 which decreases collagen production
What types of lasers can be used for scars?
Pulse dye (585-595), Nd:YAG (1065), Resurfacing (CO2 fractionated, vs ablative)
When should a pulsed dye laser be considered for scars?
Red, hyperemic, pigmented, or hypertrophic scars and keloids
What is the function of pulsed dye lasers on scars?
Promotes scar remodeling gas a result of nonspecific heating of dermal collagen. With redness, some improvement 2/2 dermal vessels
What is the purpose of Nd:YAG laser for scar treatment?
Noted to improve pigmentation, vascularity, pliability, and height of keloids, and hypertrophic scars
What is the mechanism of scar improvement using ablative lasers?
- Ablates stratum corneum and some of superficial dermis
- Is good for re-contouring > dermabrasion, dermal heating leads to remodeling
How is radiation used for scars?
Shouldn’t be used in monotherapy, used with excision often (15-20 Gy in 5-6 sessions)