SBAs Flashcards

1
Q

What are onset/offset of a volatile related to?

A

The blood:gas partition coefficient.

The lower the coefficient, the faster the onset.

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2
Q

What is volatility of a volatile anaesthetic related to?

A

It’s related to the boiling point.

The lower the BP the higher the volatility.

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3
Q

What does potency of a volatile gas relate to?

A

Potency relates to oil:gas partition coefficient and MAC.

The higher the oil:gas partition coefficient/lower the MAC - the greater the potency.

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4
Q

How does botox work?

A

Botulinum toxin is an exotoxin produced by the anaerobic bacterium Clostridium botulinum and now used as a therapeutic drug.

It inhibits acetylcholine release from nerve terminals.

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5
Q

How does clarithromycin work?

A

It’s a macrolide- these inhibit protein synthesis by binding to the ribosome and interfering with translocation

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6
Q

What happens to the RMP as potassium ions move out?

A

Becomes more negative

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7
Q

What happens to the RMP as potassium moves into the cell?

A

Becomes more positive

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8
Q

Why, in the fetus, does blood supplying the brain have a higher oxygen content than blood supplying the trunk and lower limbs?

A

Because the blood with a higher O2 content flows preferentially across the foramen ovale and is ejected via the left ventricle into the carotid arteries

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9
Q

What does the ductus venosus do in the fetal circulation?

A

ensures that a majority of oxygenated blood from the umbilical vein bypasses the portal hepatic circulation

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10
Q

What does the ductus arteriosus do in the fetal circulation?

A

Ensures that most of the blood ejected from the pulmonary artery bypasses the collapsed fetal lungs

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11
Q

What do the dorsal columns of the spinal cord convey?

A

Fine touch, proprioception and vibration sensations are all conveyed in the dorsal column tracts.

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12
Q

How long is succinylcholine safe for after burns?

A

24hrs

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13
Q
A
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