SaSx Test 2 Flashcards
2 main indications for incisional biopsy
Suspect false negative from FNA
If Tx is likely altered by results
Orientation of incision for incisional biopsy
parallel to lines of tension
Tru-Cut incisional biopsy
14, 16 or 18G
any accessible mass
sedation or local anesthetic bc tumor has poor innervation
Punch incisional biopsy
> 6mm for diagnostic sample
do not use for hypodermal masses - risk undetected hemorrhage
can punch out entire mass if small
Wedge incisional biopsy
ulcerated or necrotic tissue or deeply located masses
entire biopsy tract must be removed later
use gelpi retractors to maintain tissue retraction for deeper lying tissues
Gelpi retractors
retract tissues for deep wedge incisional biopsies
Excisional biopsies
post treatment, if invasive or high risk to get biopsy
prevent seeding, eliminate dead space, don’t drain
Pseudocapsule
reactive zone, microscopic extensions of satellite tumor cells
Enneking Classification
intralesional - debulk lipomas
marginal - breach pseudo capsule; extremities, eyes, perianal region
Wide - excise around pseudocapsule
Radical - remove entire body compartment
Mast Cell tumor margins - 2 methods
1) Fulcher - mark out 1, 2 and 3cm from tumor. 100% clean for gr I and II at 3cm and 2 fascial planes deep (grade dependent)
2) Pratschke Modified - widest diameter of tumor = your lateral margin (unless >4cm is always 4cm), 1 fascial plane deep
benign tumor resection margins
1cm lateral and 1cm deep
Inking of biopsies
ink all cut surfaces, let dry 15-20 mins before setting in formalin
Davidson dye - yellow or black
Biopsy submission
incomplete bread loafing
formalin:tissue = 10:1
small samples in cassettes
tissue 0.5-1cm thick
Holding layer of the stomach?
submucosa
_________ resection may be needed when doing a ventral midline celiotomy.
Falciform ligament
Used for retraction in stomach surgeries
Balfour retractors
T/F: the best suture material to close the stomach is braided.
False, don’t use braided
Closure of the stomach (hint, its two layers)
Double inverting Cushing (serosa, muscularis, submucosa) oversewn with Lembert (serosa + muscularis)
Most common indication for a gastrotomy
Gastric foreign body
3 predispositions to pica
- Iron deficiency
- Hepatic encephalopathy
- Pancreatic exocrine insufficiency
Gastric foreign bodies
Dx of choice: RADS
- do rads right before Sx because FB can move
Tx w/ gastrotomy - incise ventral hypovascular area between greater and lesser curvature, lavage with sterile saline (98.6-101.2F)
What is FALSE regarding Congenital Pyloric stenosis?
A) seen commonly in brachycephalics + siamese cats
B) involves hypertrophy of the mucosa of stomach
C) Treated with pyloromyotomy or Transverse Pyloroplasty
D) Clinical signs evident at weaning
B IS FALSE - involves hypertrophy of the circular mm of muscularis layer
Pyloromyotomy
Fredet-Ramstedt procedure
Tx congenital pyloric stenosis
1-2cm incision through serosa and muscularis
Transverse pyloroplasty
Heineke-Mikulicz procedure
Tx congenital pyloric stenosis
3-5cm full thickness incision over pylorus, orient incision transversely and close w/ appositional pattern
A puppy comes into your clinic presenting with intermittent vomiting. Owner tells you he just got the puppy from a breeder who mentioned the puppy had just been weaned. What is your diagnostic test of choice?
A) Rads to look for foreign body
B) Endoscopy to look for mucosal hyperplasia
C) ELISA to look for phycomycosis
D) Contrast rads to look for congenital pyloric stenosis
D - look for apple core sign
A 10y old male intact Shih Zhu is brought to your clinic because he has been vomiting. You conduct abdominal US and notice the muscularis of his stomach is 6mm and the pyloric wall is 10mm in thickness. What do you suspect? What are 2 surgical corrections you can potentially do?
Chronic hypertrophic pyloric gastropathy (CHPG)
- hypertrophy of mucosa and muscularis (normal thickness are <4mm for muscularis and <9mm for pyloric wall)
Two possible Sx:
1) Y-U Advancement pyloroplasty
2) Bilroth I - Gastroduodenostomy
Y-U Advancement Pyloroplasty
single pedicle advancement to Tx chronic hypertrophic pyloric gastropathy
Pro: inc diameter of pylorus, access to excise hypertrophied mucosa
Con: potential necrosis of flap tip (make sure it is a U and not a V)
Bilroth I
Gastroduodenostomy
- remove portion of pylorus including pyloric sphincter and reattach stomach + duodenum
Pro: all dz tissue can be removed
Con: technically demanding, inc risk dumping syndrome + reflux gastritis
Phycomycosis
Gulf coast states, transmural thickening, gastric outflow area, eosinophilic pyogranulomatous infection
antifungals do not work
very poor prognosis
You live in Florida and a dog comes into your clinic with signs of vomiting and diarrhea. You palpate a thickened mass in its abdomen where its stomach is. You perform an ELISA and it reveals P. insidiosum antibodies. What is your next course of action?
A) Give antifungals for 4w
B) hug your client and say sorry because this dog is a goner
C) Gastrotomy
D) It is self limiting, no tx necessary
B - very poor prognosis, this dog will likely die in a month (antifungals DONT work)
Billroth II complications (3)
Gastroenterostomy
1) alkaline gastritis
2) blind loop syndrome
3) marginal ulceration
How can you assess gastric viability?
gastric wall thickening - slip
serosal surface colour
capillary perfusion
peristalsis (pinch it)
Poster breed for GDV?
great danes
T/f: GDV is predisposed in a dog that has a primary relative that has the disease
True
Most common type of gastric displacement
Clockwise torsion (<180)
A dog comes in with GDV (oh no)! You open it up and notice the stomach is covered by omentum. Which way did the stomach turn?
Clockwise (omentum doesn’t cover stomach if counterclockwise)
A large dog comes into your clinic and collapses. You ask the owner to describe any clinical signs leading up to their visit. The owner says the dog was vomiting, drooling, and seemed weak. He was also in a “praying posture”. What do all of these CS lead you to suspect?
GDV
What is the first goal of treating a dog with GDV? A) Untwist the stomach B) Splenectomy C) Stabilization D) gastric decompression
C - stabilize CV, resp and renal systems
What are the best and worst views to visualize GDV on rads?
Best - R lateral, see punching glove stomach
Worst - ventral dorsal, can predispose to reflux or aspiration
What drug can be used as a free radical scavenger for a dog with GDV?
Lidocaine
Which of the following is FALSE regarding surgical management of GDV?
A) Gastropexy prevents dilation and volvulus of the stomach
B) push down on funds with R hand, grasp antrum w/ L hand and rotate counter clockwise
C) spleen should be evaluated
D) confirm proper reduction by assessing gastroesophageal junction
A is false, gastropexy prevents volvulus but does NOT prevent dilation!
Recurrence of GDV with and without gastropexy
without gastropexy - 50%
with gastropexy - 4%
doesnt prevent dilation
Which is TRUE regarding gastropexy and GDV?
A) prevents dilation of stomach
B) circumcostal involves seromuscular flap around 14th rib
C) can be done prophylactically in high risk breeds
D) reduces risk of GDV to 50%
C is true
A) - doesnt prevent dilation
B) - is around 13th rib
D) reduces risk of GDV to 4%
Post op GDV deaths occur: A) never B) 1st day C) first 4 hours D) first four days
D - first four days
MC arrhythmias associated with GDV? When do you treat and with what?
Ventricular arrhythmias
Tx if Vtach >180-190bpm, pulse deficits, weakness, multifocal PVCs
Lidocaine bolus or CRI (monitor ECG)
Prophylactic antibiotic of choice for intestinal surgery
Cefazolin
What suture pattern is great to minimize mucosal eversion (intestinal surgery)?
Modified Gambee
Principles of transverse wedge intestinal biopsy
<20-25% circumference
full thickness
3-4mm wide
perpendicular to long axis
Difference between the vomiting pattern in a proximal and distal small intestinal obstruction.
Proximal (duodenum or proximal jejunum) - persistent vomiting
Distal (distal jejunum, ileum, ileocecal junction) - occasional vomiting
A 8m old kitten presents with vomiting, depression, and painful abdomen on palpation. You do rads and notice the small intestine is plicated. What do you suspect?
Linear foreign body
Important spot to check on any cat with a linear foreign body
Under the tongue
Where should you remove a non-linear small intestinal foreign body during a complete abdominal exploratory?
A) Aboral to foreign body on the anti mesenteric axis
B) Aboral to foreign body on the mesenteric axis
C) Oral to foreign body on the anti mesenteric axis
D) Oral to foreign body on mesenteric axis
B - Aboral on mesenteric axis
Typhlectomy
removal of the cecum
Classic US lesion associated with intussusception
target lesion
Which is FALSE regarding intussusception?
A) manual reduction increases risk of tearing the serosal layer
B) enteroplication prevents recurrence
C) more common in older dogs
D) resection and anastomosis is done if reduction not possible
C - it is more common in puppies
Mesenteric volvulus
German Shepherds
rare, often fatal
intestines twist on mesenteric axis, ischemia
non-responsive to oronasogastric intonation
Tx w/ rapid fluids, resection/anastamosis if possible
Begin intestinal anastomosis at the ________ border
mesenteric
How do you leak test an intestinal resection/anastamosis procedure?
occlude intestine proximal and distal, inject saline until evenly distended, gently compress, look for leaks
Methods to manage intestinal luminal disparity during an anastamosis?
cut segment at angle
space sutures closer together on smaller segment
fish mouth or Cheattle incision
place mesenteric + anti mesenteric sutures
Highest bacterial population: A) Small intestine B) Stomach C) Large intestine D) ross university gym
C - large intestine
Where is a colopexy done?
Left side of abdomen, attaches the descending colon to transversus abdominis
2 Indications for colopexy
recurrent rectal prolapse or perineal hernia
Another name for feline progressive dysautonomia (large intestine)
Key-Gaskell
Suspected reason that you preserve the ileocecal valve during a colectomy?
prevent bacterial overgrowth
T/F enemas and stool softeners improve efficacy of a colectomy as a treatment for megacolon
False, Sx is already contaminated so this is a baaaad idea
tx of choice for megacolon
Colectomy
When are post op complications most likely to occur after a colectomy tx for megacolon? A) Day 1 B) Day 2-3 C) Day 3-5 D) Never
C - day 3-5
You are going to do a colectomy to treat a kitty with megacolon. What is the antibiotic you are going to give prophylactically (considering the fact that you are dealing with a fecal ridden area)? A) Doxycycline B) Penicillin C) Metronidazole D) Cefazolin
D - Cefazolin is prophylactic AB of choice for intestinal surgery
4 risk factors for dehiscence after intestinal surgery
1) ingest foreign body or trauma
2) pre-op albumin <2.5g/dL
3) post op increase of band neutrophils
4) pre-op peritonitis
A client comes in because their dogs bum looks “messed up.” You perform a PE and notice what appears to be tissue protruding from the dog’s anus. You decide to conduct a probe test. The probe is passed completely through. What does this mean?
Intussusception - surgical emergency!
Perianal fistula
German shepherds, immune mediated cause
Tx w/ cyclosporine
Rectal adenomas
distal rectum
always submit excised mass, 25% come back as more aggressive tumor
Which of the following is FALSE regarding surgical approaches to colorectal adenocarcinoma?
A) Anal - lesions of caudal rectal or anal canal
B) Dorsal - anal canal
C) Rectal pull through - midrectal or distal colonic not approachable through abdomen
D) Swenson’s pull through - extend beyond peritoneal reflection into abdominal cavity
B - dorsal is for midrectum but not anal canal
T/F: it is okay to excise the external anal sphincter
False, dissect around it
Anal sac disease is most common in what sized dogs?
small ones (poodles, chihuahuas)
How would you decide to do an open or closed anal sacculectomy?
Closed - tumors or infected glands
Open - not common, for ruptured sacs
2 words that describe treatment of perianal gland adenomas (male intact dogs hint hint)
Castration + resection
Apocrine Gland Adenocarcinoma
Paraneoplastic hypercalcemia, PU/PD, renal failure
Px: no mets - 16-18m, mets <1y
Safest division to do hepatic surgery?
Left division
R has a lot of vasculature, central has gall bladder
The closer the injury to the liver hilus, the ______ chance of needing surgery
greater
Bile duct stunting is used to relieve obstruction due to
extraluminal compression
If an animal has necrotizing cholecystitis and the gall bladder ruptures, it will have ________
septic peritonitis
Which is FALSE regarding biliary mucoceles?
A) older dogs, breeds = shelties and cocker spaniels
B) Hyperplasia of mucus secreting cells so excessive mucus secretion
C) Classic kiwi sign on ultrasound
D) labs will show decreased liver enzymes
D - liver enzymes will be increased
Tx of choice for a biliary mucocele?
cholecystectomy - take out gall bladder
Cholecystoduodenostomy
Biliary diversion
- initial size of stoma 2.5-3cm long to dec risk of gallbladder becoming impacted w/ ingesta (causing cholangiohepatitis or cholecystitis)
Abdominal effusion that is diagnostic for bile peritonitis?
effusion bilirubin >2x serum bilirubin
For cholecystectomy, where should you transect?
at cystic duct
2 organs not drained by liver? what are they drained by?
Kidneys and adrenals
phrenicoabdominal vein
You are doing an exploratory laparotomy on a yorkie, and notice a large vessel entering the caudal vena cava cranial to the vein draining the adrenal glands. What is the significance of this vessel?
This is likely an extrahepatic portosystemic shunt
- signalment and because the phrenicoabdominal vein (drains adrenals) should be the most cranial vein entering the caudal vena cava
2 veins commonly associated with extrahepatic PSS
left gastric and splenic veins
Intrahepatic PSS
large breeds (labs, goldens, aussies, OES) - patent ductus venosus
Portal vein atresia
ascites, hypoproteinemia
No Sx, only medical management
You are conducting a necropsy on a dog. You notice there are multiple small vessels around the kidneys that appear to be connected to the liver. Which of the following is likely TRUE?
A) This dog shows evidence that it had systemic hypertension
B) This dog shows evidence that it had portal hypertension
C) This dog shows evidence of kidney failure
D) This dog has a intrahepatic shunt
B - multiple acquired shunts are caused by diseases associated with portal hypertension
A middle aged Schnauzer comes into your clinic for a routine check up. The owner mentions the dog seems to be more sensitive to drugs (not sure how the owner knew but very good finding)! You run some liver tests and blood work and find the following:
- bile acids slightly elevated
- protein C >70%
- nuclear scintigraphy - shunt fraction near normal
What is the likely diagnosis?
portal vein hypoplasia
Multiple acquired liver shunts are a result of?
vestigial embryonic communications that can open up to prevent lethal portal hypertension to develop
Cat presents with copper irises, hyper salivation, aggression and a palpable thrill in the abdomen (Bruit). What is likely?
Macrovascular shunt
What is TRUE regarding ammonium biurate crystals? A) Evident on rads B) Associated with macrovascular shunts C) Common finding in all dogs D) Associated with microvascular shunts
B
A- not seen on rads
C - only normally seen in Dalmatians
D - I made this up
A non-invasive way to document PSS?
nuclear scintigraphy