SaSx FINAL - old material Flashcards
4 classifications of operative wounds
Clean - created in Sx, no infection
Clean-contaminated - Sx created but hollow viscus or organ w/ bacteria open, no contents spilled, minor break in technique
Contaminated - Sx but gross spillage in hollow viscus organ, minor break in technique
Dirty - implies infection
Risk of infection ______ every hour
doubles
MC source of surgical wound infection
patients endogenous flora, skin and GIT
Prophylactic antibiotic for wound contamination
Cefazolin IV, 30-60 min prior to incision, q90-120 mins intraop
Therapeutic antibiotics for wound contamination
continue 2-3d after resolution of infection
4 stages of wound healing
- Inflammation
- Debridement
- Repair
- Maturation
Inflammatory phase of wound healing
0-5 days
initiated by tissue damage, hemorrhage = 1st response to injury
vasoconstriction - fibrin clot - vasodilation + inc vascular permeability - leukocyte response (macrophages), platelets
WBC leaking from vessels into wound initiates debridement phase
Debridement phase of wound healing
2-5 days
neutrophils and monocytes initiate debridement phase
monocytes = primary cells for wound healing
macrophages - secrete collagenases to remove necrotic tissue, secrete chemotactic + growth factors, recruit mesenchymal cells
Repair phase of wound healing
3-5 days to 2-4 weeks
macrophages stimulate fibroblast and DNA proliferation
acidic + oxygen rich environment
Granulation tissue - barrier to infection, source of special fibroblasts, surface for epithelial migration
Epithelialization + wound contraction
Maturation/Remodelling phase of wound healing
strength of wound optimized d/t changes in the scar, collagen I increases, III decreases
most rapid gain in strength 7-14d post injury
Golden period of wounds
within 6 hours - insufficient microbial replication to cause infection, can usually manage with primary closure
T/F: alcohol is ideal to flush open wounds
false, damages open tissue, never use
Preferred lavage
sterile isotonic saline or LRS
7-8psi (1L saline bag w/ pressure cuff at 300mmHg)
Number one choice for empirical antimicrobial selection to treat a contaminated wound
Clavulanic acid - potentiated amoxicillin (clavamox)
2 antibiotics that you should take a culture before using
fluoroquinolone and aminoglycosides
Compare TAB to silver sulfadiazine
TAB (Triple Antibiotic Ointment)
broad spectrum, prevention, not effective vs Pseudomonas
can retard wound contraction
Silver Sulfadiazine
DOC for wounds, can tx most gram + and - including Pseudomonas
combine w/ aloe vera to reverse wound retardant effects
Layered vs En Bloc debridement
Layered - MC, excise contaminated SQ (careful in cats can delay wound healing), remove isthmus connections, excise in layers
En Bloc - entire wound excised then closed primarily
Debridement mechanism that is highly selective for devitalized tissue only: A) Layered B) En Bloc C) Autolytic D) Biosurgical
C) autolytic
A dog comes in with an infected wound. The owner said they tried to bandage it but it started smelling like tortillas so they came to the vet. You pull off the bandage and notice blue green pigment on the bandage. What is at the top of your differential list?
Pseudomonas. TAB wont work, will need silver sulfadiazine.
Penrose Drain
passive
fluid travels along drain not inside, don’t fenestrate, MC drain in vet med
remove 5-7d later or risk ascending infection.
daily bandage changes, don’t rely on owner
warm compress to promote drainage, not cold compression
don’t do double exit passive drain
make sure adequately clipped + prepped
Jackson Pratt drain
active
fluid travels inside fenestrated tubing, exits dorsal to wound
strict aseptic technique for placement
aggressive en bloc debridement before closure
remove when fluid: 5ml/kg/d or 0.2ml/kg/h
Modified butterfly catheter
small animals or wounds in challenging areas
Most common used bandage in vet med A) adherent B) non-adherent C) Occlusive D) Semi-occlusive
D - semi-occlusive, allows air to penetrate + exudate to escape from wound surface
Can you use a wet to dry bandage on granulation tissue?
No! Will disrupt healing tissue when removed
Match the moisture retentive dressing (MRD) with the exudate level.
Dressings: calcium alginate, hydrocolloid, hydrogel, polyurethane foam
Exudate feel: high, moderate, moderately high, low to minimal
Calcium alginate - high
Moderately high - polyurethane foam
Moderate - hydrocolloid
Low - hydrogel
T/F: all bite wounds are contaminated
true
4 depths of burns
1) superficial - 1st degree, outermost epidermis, moist, painful
2) Partial thickness - 2nd degree, epidermis + dermis, oedematous, painful, marked inflammation
3) full thickness - 3rd degree, epidermis + dermis, dark brown, non-painful, eschar
4) extension beyond dermis - 4th degree, needs Sx
Who described gentle tissue handling?
Halsted
4 types of pivotal skin flaps
1) rotation
2) transposition
3) interpolation
4) distant
Axial pattern flaps
rely on direct cutaneous artery + vein at base of flap
- caudal superficial epigastric
- thoracodorsal
also, cranial superficial epigastric, vehicular, deep circumflex iliac
A flap composed of skin with muscle, bone or cartilage
Composite flap
Skin grafts
Phase I - 0-72h - contraction of fibrin strands, graft pulled closer to bed
Phase II - 72h-10d - fibrin to fibroblasts, leukocytes, phagocytes (fibrous adhesion)
1) plasmatic imbibition
2) inosculation
3) revascularization
Nephrolithiasis
Ca oxalate + struvite
PE: abdominal discomfort, hydronephrosis
Dx: rads, US (echogenicity to see which stones) check contralateral renal function prior to tx
Tx:
- Nephrolithotomy via ventral midline celiotomy, clamp time = 20 min, sagittal incision, remove stone, culture renal pelvis, flush, catheterize to ensure ureter potency. Close futureless (hold 5 mins for fibrin seal), horizontal mattress. nephropexy to minimize entrapment/torsion
- Pyelolithotomy - incise renal pelvis instead of parenchyma (if dilated or if thats where calculi is) - no occlusion needed, dec hemorrhage risk, no nephron damage
Post op - diuresis, monitor, post op rads
Renal Trauma
CS: hematuria
Dx: contrast excretory urography - see contrast media leak into abdomen (uroabdomen)
Tx:
- minor: conservative
- moderate: Sx repair + omental patching
- severe: nephroureterectomy - ensure other kidney functioning
Hydronephrosis
dilation of renal pelvis + atrophy of renal parenchyma
death if bilateral
Dx: US
Tx: <1w obstruction = resolution, >4w = may regain 25%, nephroureterectmoy
Pyelonephritis
predisposed by damaged parenchyma
Tx: nephroureterectomy
Giant Kidney worm
Dioctophyma renale, fish or frog consumption
Tx: nephrotomy if early enough to cut out worm, otherwise nephroureterectomy
Renal neoplasia
mostly malignant, MC benign = renal adenoma
renal cell carcinoma - male dogs, older, MST 9m. Tx: nephroureterectomy + chemo
Renal lymphoma - MC cats, chemo
Embryonic nephroblastoma - congenital, young (4m), MST 6m - very aggressive
Dx: US best
Tx: exploratory laparotomy, check for metastatic lesions,, preferred Bx method, unilateral nephroureterectomy
Renal Biopsy
high risk of hemorrhage, only do if worth the risk
dont do if coagulopathies, hypertension, chronic hydronephrosis
sample CORTEX not medulla
collect at least 2 samples
US guided = preferred
Renal transplants
rare in dogs, more common in geriatric cats w/ chronic renal dz or failure, expensive
immunosuppression required
owner must adopt + take care of donor
Ectopic ureter
extramural or intramural
female young husky
CS: incotinence (difficulty potty training)
Dx: excretory urography, CT, US - ureter depositing urine in wrong place
Tx: neoureterocystostomy - transplant distal ureter to new place in bladder
- intramural (MC) - perform cystotomy + create new stoma @ level of trigone
- extramural - ligate + transect then place through cystotomy incision
difficult Sx but good Px
Ureterocele
persistent membrane in embryonic development over ureteral orifice
Dx: IV urography - cobra head sign
Tx: intravesicular - ureterocelectomy (remove ureterocele), ectopic - neoureterocystostomy w/ ureterocelectomy
Ureteral Trauma
#1 cause iatrogenic (OHE Sx) Dx: IV urography - localizes lesion Tx: nephroureterectomy (make sure other kidney functional
Ureteroureterostomy
tx damage to more proximal ureter, resection + anastomosis = difficult
Urinary diversion
can’t have urine going through damaged ureter
Ureteral stent - pig tail catheter proximal to anastomosis through bladder to urethra, remove in 5-7d
Nephrostomy tube - divert urine, fenestrated tube from kidney to renal pelvis –> outside patient
Loss of ureter length technique that involves anastomosis of one ureter to the other
Transureteroureterostomy
Urolithiasis
MC indication for ureteral Sx, cats
dx: rads - most radiopaque CaOx, US - dilation of ureter/pelvis
Tx: cystotomy + retrograde flushing + removal via pyelithotomy
Persistent Urachus
urine dribbling from umbilicus, patent urachal canal
omphalitis (umbilical inflammation)
Tx: Sx removal of urachal tube, ventral midline incision
Vesicouracheal diverticulum
MC urachal abnormality in dog
external opening closed, bladder attachment patent, predisposes patient to uroliths + UTI
Dx: positive contrast cystography
Tx: partial cystectomy + diverticulectomy
Bladder rupture
trauma (HBC), iatrogenic (catheterization)
Dx: positive contrast urethrocystogram is best - see leakage of contrast into abdomen. US - free fluid, rads - abdominal fluid + absence of bladder. Abdominocentesis - urea in fluid = serum urea, Creat in fluid > serum creat
Tx: stabilize, then urinary diversion - tube cystotomy w/ cystopexy –> then Sx
VD approach to exploratory laparotomy, check for concurrent injury, close bladder wall + omentalize or serosal patch, place catheter in urethra
Cystic calculi
common, bladder MC, struvite + Ca oxalate
Dx: rads - can see struvite + CaOx (cystine + urate = radiolucent), double contrast cystography - can see urate (Dalmatians!)
Tx: non surgical - hydropropulsion, transurethral cystoscopy, diet (struvite only), electrohydraulic lithotripsy
Sx: cystotomy - MC sx of bladder, ventral approach preferred, don’t cut lateral ligaments, close w/ simple continuous + inverting, can also do one or two layer inverting pattern, leak test, post op rads
Polypoid cystitis
uncommon, middle aged female dogs, resembles TCC but non-neoplastic, hematuria when polyps rupture
Bladder tumors
Dog: uncommon, TCC MC, 97% malignant, old Scottish terriers, trigone
Cat: rare, bladder 2nd MC site for UT tumor (renal lymphoma #1), TCC MC bladder tumor, middle aged males, apex
Transitional cell carcinoma
obesity predisposes
Dx: rads, US, transurethral Bx, bladder tumor antigen test - AVOID FNA (readily exfoliates = tumor seeding)
Tx: partial cystectomy w/ >1cm borders, chemo, poor Px
hypospadiasis
MC developmental abnormality of male genitalia, incomplete formation of penile urethra, Boston terriers
Urethral prolapse
protrusion of urethral mucosa through orifice, young male brachycephalics
PE: bleeding from prepuce, licking, red-purple mass
Tx: mild: reduce + purse string or urethropexy
severe - resection + anastomosis
urethral trauma
Dx: positive contrast urethrogram
Tx: urinary diversion w/ urethral catheter or cystotomy tube if incomplete or small laceration, complete rupture –> anastomosis or repair w/ urinary diversion
Urethral obstruction
common in dogs + cats, male > females
dog: ischial arch + caudal to os penis, stones
cat: distal 1/3 urethra, mucus plugs, crystals, stones
Dx: rads
Tx: cystotomy after hydropulsion, urethrotomy if unsuccessful (temporary opening in urethra)
Urethrostomy = permanent opening of urethra at new site, dogs = scrotal, cats = perineal
Vestibulovaginal stenosis
CS: vaginitis, UTI, painful breeding, hydrocolpos
Dx: aseptic exploration, contract rads, <0.2 = severe stenosis. Vaginoscopy = best, direct visualization
Episiotomy
incision of vulvular orifice to access vestibule + vagina
Recessed vagina
conformational abnormality, vulva engulfed by skin
medium/large overweight dogs, early OHE not a cause
CS: skin fold dermatitis, vaginitis, recurrent UTI incontinence
Tx: cleansing, weight loss, episioplasty
Vaginal hyperplasia
inc estrogen levels during proestrus/estrus
<2y large breeds, one of first 3 cycles, mucosa protrudes from vulva, tissue from ventral vaginal floor
Tx: conservative management, E collar, resolves at end of tissue, OHE to prevent
Vaginal prolapse
donut shaped appearance
Tx: manual reduction, hyperosmotics, OHE
Ovarian Remnant syndrome
recurrence of estrus after OHE, dogs> cats
CS: vulvular enlargement,t attraction to males, vaginal cytology mimics heat cycle
Tx: Sx, usually at caudal pole of kidney, avoid ureter
Dystocia
can’t expel fetus, 75% maternal cause
primary uterine inertia - parturition fails, birth canal/fetus = normal, no neonates born. CS = prolonged gestation
secondary - uterine fatigue
tx: primary w/ oxytocin, c section if doesnt work or secodnary
C sections
incision midway b/wn xyphoid + umbilicus to cranial pubis, exteriorize uterus, pack w/ lap sponges, perform hysterotomy
clamp umbilical cord 2-6cm
if hemorrhage or involute not started, oxytocin IM
remove puppies <60s if en bloc resection
Testicular torsion
rare, abdominal, inguinal or scrotal
CS: anorexia, lethargy, shock, death
Dx: US + doppler, flow absent
Paraphimosis
inability to retract penis into prepuce, congenital or acquired, can lead to necrosis
Tx: lube, hyperosmolar agents, preputiotomy, preputial advancement
recurrent - phallopexy, amputate penis if necrotic
Phimosis
inability to protrude penis
Tx: enlarge preputial orifiice
Prostatic cysts
accumulation glandular secretions in prostate of older intact males
CS: related to caudal abdominal ass, asymptomatic, distension, incontinence + dysuria
Dx: palpation, rads, US, FNA
Tx: if small, Sx + castration, if large, resection, drainage, omentalization, castration
Benign prostatic hypertrophy
aging, inc sensitivity to testosterone receptors
CS: asymptomatic, dyschezia, ribbon feces
rectal: symmetrical, large, no pain
Tx: castration