Sarocoidosis Flashcards
Sarcoidosis involvement of which organs needs urgent treatment?
Heart
CNS
Eyes
What is Lofgren’s Syndrome?
- Bilateral hilar lymphadenopathy
- Erythema nodosum
- migratory polyarthralgis
- fever
Can FORGO biopsy - high likelihood of spontaneous remission.
What is Heerfordt’s syndrome?
- Anterior uveitis
- Parotid enlargement
- Facial Palsy
- Fever
What are the 4 stages of sarcoidosis?
(1) Bilateral Adenopathy
(2) Adenopathy w/Parenchymal Lesions
(3) Parenchymal Lesions w/no Adenopathy
(4) Fibrosis
What are the cardiac manifestations of sarcoidosis?
Cardiomyopathy
Arrhythmia
Heart Block
What are the neurological symptoms seen in sarcoidosis?
Cranial Nerve Palsy Headache Ataxia Weakness Nonspecific lymphocytic inflammation on LP
What are the cutaneous manifestations of sarcoidosis?
Lupus Pernio - Pathopneumonic for sarcoidosis.
Erythema Nodosum
What do you need to rule out in sarcoidosis?
HIV
TB
What are the indications to treat sarcoidosis?
(A) Pulmonary Indications
- Bothersome symptoms (cough, dyspnea)
- Deteriorating lung function by PFTs
- Pulmonary HTN
(B) Extra-pulmonary
- Eye disease, hypercalcemia, symptomatic liver disease, severe skin disease, CNS & cardiac involvement
How would you treat mild respiratory symptoms in sarcoidosis?
Treat cough and stable PFTs with inhaled steroids.
How do you treat erythema nodosum in sarcoidosis?
Usually has a good response to NSAIDs.
How long would you treat someone with sarcoidosis with oral prednisone for?
Usually treat for 1-3 months at initial dose, with slow taper for about a year.
