Sarcoidosis Flashcards
What is sarcoidosis?
Multisystem NON CASEATING granulomatous disorder of unknown cause
How systems does sarcoidosis affect?
Bilateral hilar lymphadenopathy (BHL)
Pulmonary infiltrations
Ocular lesions
Skin lesions
How systems does sarcoidosis affect?
Bilateral hilar lymphadenopathy (BHL)
Pulmonary infiltrations
Ocular lesions
Skin lesions
Symptoms of sarcoidosis?
Dry cough
SOB
Weight loss
Signs of sarcodosis?
Erythema nodosum
Lupus pernio
Uveitis
BHL + pulmonary infiltrates or fibrosis
Investigations for sarcoidosis?
Serum ACE - raised
Ca2+ - raised
CXR - BHL + pulmonary infiltrates/fibrosis
MRI - CNS involvement
What is Lofgren’s?
Specific presentation of sarcoidosis
Triad of:
Erythema nodosum
Bilateral hilar lymphadenopathy
Polyarthralgia
Gold standard for diagnosis?
Histology from biopsy via bronchoscopy - non-caseating granuloma with epitheloid cells
Management of sarcoidosis?
No/mild symptoms = no treatment as will resolve spontaneously
Moderate/severe symptoms = steroids