Samplex Flashcards
Proteins destined to be secreted or targeted out of the plasma membrane are processed in the…
Rough ER
This protein attaches to membrane proteins destined for endocytosis and eventual degradation in the lysosomes
Ubiquitin
Type of diffusion where carrier undergoes conformational change:
Facilitated diffusion
Co transport molecule of glucose
Sodium
Used for cholesterol uptake
Receptor- mediated endocytosis
A form of bull transport by which a hormone is secreted when the appropriate signal is received by the cell is:
Regulated exocytosis
Phosphorylation of g protein coupled receptor results in
Inactivation of receptor
Activation of this effector g protein results in the activation of creb protein
Adenylyl cyclase
Activation of plc results in an increase of cytosolic calcium because of the opening of
Ip3 gated calcium channels in the er
Store operated calcium channels
Binding of a ligand to a tyrosine kinase receptor causes
Autophosphorylation of the receptor
Cytokine receptors acitvate loosely associated tyrosine kinases known as
JAK
Transcription factor activated by receptor serine-threonjbe kinase
SMAD
Phosphorylated insulin receptor can activate this
MAPK
Receptor for ligand epinephrine
G protein coupled receptor
Receptor for estrogen
Intracellular
Receptor for TGF-B
Serine threonine kinase receptor
Neuron that sends impukses towards the cns
Afferent unipolar
In rmp, ions move through which channel
Leak channels
Local potential exhibited by a sensory neuron
Generator potential
Equation on concentration of ions in rmp
Goldman
Hodgkin
Katz
The spike potential determines this neuron property
Excitability
The duration of action potential is the
Spike potential
The critical firing level
Threshold potential
Hyperpolarization occurs during what period
Relative refractory period
Toxin that blocks voltage gated sodium channels; from puffer fish
Tetrodotoxin
Toxin blocks nmj ach receptor; from snake venom
Bungarotoxin
Blocks voltage gated potassium channels
Apamin from honeybee
Viltage gated sodium channel is most dense at the
Nodes of ranvier
Susceptibility trend to hypoxia
B>A>C
Neuron fiber susceptibility to pressure
ABC
Neuron fiber susceptibility to local anesthetics
CBA
Increases the likelihood of an action potential on the PSN
Temporal and spatial summation
Is the simultaneous firing of neurons
Spatial summation
Increasing the frequency if stimulation of the neurons
Temporal summation