Salivation and swallowing Flashcards
What are the functions of saliva?
• Hydrate food
• Aids movement of tongue during speech
o Mucins (glycoproteins) help with the lubrication
• Keeps teeth healthy due to saliva having antibacterial properties
• Saliva acts as first line of defence against pathogenic food that has been injested
• Saliva is a solvent that can dissolve flavour molecules
• It begins the process of digestion (amylase and lingual lipase)
• Transmits infection
What is the medical word for reduced flow of saliva in the oral cavity and what are its consequences?
xerostomia
- get a VERY dry mouth
- Can cause difficulty swallowing, mouth ulcers, dental cavities and oral candidiasis, bad breath
Why can xerostomia cause oral candidiasis?
because there is no saliva there to protect the mouth against the fungi
What causes xerostomia?
drug side affects (SSRI)
blocked noses and breathing through mouth
radiotherapy to head
salivary gland surgery
What is the composition of saliva?
- mostly water
- has potassium and bicarbonate
- IgA
- lysozyme
- lactoferrin
What is the function of K+ and HCO3- in the saliva?
makes it slightly acidic (pH 8)
What do IgA do in the saliva?
secrete immunoglobulin
What does lactoferrin do in the saliva?
-sequesters iron meaning it holds on to it so bacteria don’t get to it
How is saliva made hypotonic?
- ductal modification where more ions are reabsorbed from saliva than secreted
- the ductal cells are relatively impermeable to water
- the overall effect is more ions are removed from saliva than water
- tonicity varies the flow rate
What salivary glands are the largest?
parotid glands
Where are the parotid glands?
they pass over the masseyter muscle and pierce the buccinator
-can be found lateral t the second top molar
Where are the submandibular glands?
They open on the medial side of the most floor
Where are the sublingual glans?
they open on the later side of the mouth
What is the neural control of the salivary glands?
-via the autonomic nervous system with the parasympathetics being the main driver of salivary secretion (increasing secretion)
What nerve are the sublingual and submandibular glands innervated by?
facial nerve
What nerve is the parotid gland innervated by?
glossopharyngeal
What do the sympathetics do?
stimulates small amounts of saliva secretion but also causes vasoconstriction if there is too much stimulation
What drugs have a side effect of dry mouth?
anti-muscarinic drugs e.g. SSRI’s
What are MUMPS?
also known as paratoiditis
-very painful