Salivary glands

Question 1

hyposalivation

Answer 1

about 2/3 of typical flow rates

- xerstomia, mucosal changes, enamel erosion, increased caries, difficulty in swallowing, changes in taste

Question 2

medications causing hyposalivation

Answer 2

anti-cholinergic, diuretics, antidepressants, antihistamines, antihypertensives

Question 3

What type of glands are salivary?

Answer 3

exocrine glands

Question 4

What is affect of salivary flow when sleeping?

Answer 4

decreases markedly

Question 5

Unstimulated salivary flow amount vs stimulated

Answer 5

0.2-0.4/min (~1mm in mouth at any time)

2-5/min when stimulated

Question 6

major salivary glands and types

Answer 6

parotid (CN IX) - 60% saliva; serous, amylase
submandibular (VII) - 25%; mixed mostly serous
sublingual (VII) - 7-8%, mixed mostly mucous

Question 7

minor salivary glands

Answer 7

von ebners (CN IX) - secretes lingual lipase
labial, palatal, buccal, lingual - secretes mucins (not exclusive but major source)

Question 8

What makes up the stroma of salivary glands?

Answer 8

capsule, septa (divides gland into lobes and lobules)

- contains fibroblasts, blood vessels, nn fibers, plasma cells, fat cells

Question 9

parenchyma components

Answer 9

acini: serous, mucous and mixed
ducts: intercalated, striated (‘secretory), excretory (collecting)

Question 10

salivary gland development

Answer 10

protrusion of epithelial cells in mesenchyme, bud formation, branching morphogenesis, branching continues; cavitation occurs (in forming ducts), terminal differentiation: maturation of ducts, then acinar cells