Salivary Glands

Question 1

Conditions of the salivary glands

Answer 1

1. Inflammatory/Sialadenitis - trauma, viral (mumps), bacterial (s aureus, strep viridans), autoimmune (Sjogren syndrome)
2. Sialolithiasis - ductal obstruction
3. Neoplasms

Question 2

Neoplasms of the salivary glands

Answer 2

• affects parotid (75%) > submandibular (10%) > sublingual & minor glands
  1. Pleomorphic Adenoma
  2. Warthin Tumour

Question 3

Features of pleomorphic adenoma of the salivary gland

Answer 3

• benign epithelial mixed tumour
• most common tumour of salivary glands, 10x more common in the parotid, 40y
• painless, slow growing mass in front of & below ear
• prone to recurrence, but malignant transformation rare

Question 4

Morphology of pleomorphic adenoma of the salivary gland

Answer 4

G:

• lobulated, unencapsulated knobbly mass
• with solid, firm, whitish, translucent chondroid cut, cartilage-like surface

M:

• epithelial components (ducts, squamous metaplasia)
• myoepithelial components
• chondromyxoid components

Question 5

Features of Warthin Tumour

Answer 5

• benign
• almost exclusively in parotid, superficial lobe
• male predominance, 50-70y

Question 6

Morphology of Warthin Tumour

Answer 6

• oval encapsulated mass
• soft, pale grey w spaces filled w milky secretions
• spaces lined by double layer of epithelial cells, dense lymphoid stroma w germinal centres