Salivary gland neoplasms Flashcards
Pleomorphic Adenoma
benign salivary gland tumours
predominantly affect the superficial lobe of the parotid gland
epithelial and ct origin
female predilection between 30-50yrs
Epidemiology of PA
60% of tumours in major and minor SG
All ages (peaks 20-40yrs)
CP of PA
Pleomorphic
Tumour forms ducts, sheets, strands of myoepithelium which produces a myxoid matrix. Tumour delineated by a thin incomplete capsule.
Benign tumour but local recurrence common.
Malignancy can occur in longstanding lesions e.g., carcinoma ex PA
benign tumour begins to metastasise
Warthin’s tumour
Benign tumour
painless, slow growing bump in front of the ear, on the bottom of the mouth, or under the chin
increase in size over time, but few become cancerous
Epidemiology WT
Common
wide age range
3M:2F
Smokers 8x more likely
CP WT
Cysts with papillary projections of bland epithelium and lymphoid background
completely benign
probably hyperplastic/neoplastic salivary elements in a lymph node
Mucoepidermoid carcinoma
common type of minor SG
MC can be found in other organs eg thyroid gland
mucicarmine staining in one stain used
Epidemiology MC
Occurs all ages
Peaks 40-50yrs
CP MC
MSGs and PGs
malignant tumour but usually low grade
high grade lesions look like adenocarcinoma NOS or even SCC
Histology MC
Circumscribed but not encapsulated
mucous cells, epidermoid cells and intermediate cells
Adenoid cystic carcinoma
ACC is relatively rare form of cancer
salivary glands
Epidemiology ACC
Occurs all ages
40-50yrs
Epidemiology ACC
Occurs all ages
40-50yrs
CP ACC
Soft encapsulated discoloured mucosa
nerve related symptoms
malignant tumour but usually low grade
widespread local invasion
famed for its perineural invasion
histology ACC
swiss cheese pattern
