Lichen Planus and Lichenoid Reactions

Question 1

Lichen Planus

Answer 1

Clinically distinctive maculopapilar mucocutaneous rash with characteristic

Question 2

LP CP

Answer 2

Violaceous papule topped with silver scale

Question 3

LP GF

Answer 3

40+ years age
F>M
2% of population

Question 4

Histopathology of LP

Answer 4

Epithelium might be hyperkeratotic, hyperplastic, atrophic or ulcerated
langerhans cells
antigens presented to t cells
t cells infiltrate back to the altered epithelium and kill individual basal cells

Question 5

Persistency of LP

Answer 5

On going and non-resolving inflammatory response widens to include other antigens on the surface of the basal keratinocytes and perpetuates through the mucosal attack by the immune response

Question 6

Difference between LP and LR?

Answer 6

OLP is a consequence of T cell mediated autoinflammatory process to a still unknown antigen
OLR might be caused by drugs, dental restorative instruments and dental plaque