Salivary gland Flashcards
How is carcinoma ex pleomorphic adenoma classified (In the CAP)?
Intracapsular (noninvasive)
Minimally invasive
Invasive
List patterns of adenoid cystic carcinoma in the salivary gland
tubular
cribriform
solid
How is polymorphous adenocarcinoma of the salivary gland classified and graded (in the CAP)?
Classic: low, intermediate, high grade
Cribriform: low, intermediate, high grade
How is intraductal carcinoma of the salivary gland graded?`
low grade, high grade (no intermediate)
What are the 3 major salivary glands?
Parotid
Submandibular (submaxillary)
Sublingual
Minor salivary glands are mucous-secreting glands in the lining membrane of the upper aerodigestive tract. Staged according to the site in which they reside (ex. oral cavity, pharynx, sinonasal tract).
List the 3 major types of salivary gland tumors that are amenable to grading:
Adenoid cystic (tubular, cribriform, solid)
Adenocarcinoma (Polymorphous - classic & cribriform, low, intermediate, high; NOS - low, intermediate high; intraductal low and high)
Mucoepidermoid (low, intermediate, high)
What is the significance of adenoid cystic, solid?
> 30% solid pattern is considered high-grade ACC
What are the characteristics and findings that influence grading in mucoepidermoid carcinoma?
growth pattern characteristics: cystic, solid, neurotropism
Cytomorphology: anaplasia, mitoses, necrosis
List the 4 dissections categorized as “selective neck dissection” for salivary gland.
(CAP protocol)
Supraomohyoid (removes lymph node levels 1, 2, 3)
Posterolateral neck
Lateral neck
Central compartment
NB. Superselective dissection removes fibrofatty elements of 2 or fewer segments.
If it is not clear/possible to assess the precise levels of the lymph nodes (eg. anatomic landmarks not specified), how are they estimated by the pathologist?
Level 2: upper third of internal jugular or neck specimen
Level 3: middle third of internal jugular or neck specimen
Level 4: Lower third of internal jugular or neck specimen
