Saliva 2

Question 1

Describe the general structure of the secretary end piece….

Answer 1

Comprised of a cluster of acinar cells surrounding a central lumen.

Question 2

The cells of the end piece are joined together by ______ which allow the passage of ______ & ____, but not _____.

Answer 2

Tight junctions, allow water and small ion passage, but not larger molecules.

Question 3

______ Surrounds the Acinar cell.

Answer 3

Myoepithelial cell

Question 4

The entire end piece is surrounded by _____.

Answer 4

Basal lamina

Question 5

Describe the 6 structural aspects of a Serous Cell.

Answer 5

1. Pyramidal in shape
2. Rest on basal lamina
3. Short irregular microvilli
4. Exhibit many characteristics of polarized protein secreting cells.
5. Secrete many enzymes and glycoproteins
6. Protein machinery is well defined (golgi app. RER….)

Question 6

Describe the 5 Structural aspects of a Mucous cell.

Answer 6

1. Cuboidal to columnar shaped
2. Oval nuclei pressed toward base (and flatten/squished)
3. Arranging in tubules around a larger central lumen
4. Secretes mucins (not secreted by serous cells)
5. Secretory granules pale staining

Question 7

What is a serous demilune?

Answer 7

A cluster of serous cells topping a mucous acinus

Question 8

_______ surround the acinar cells & intercalated ducts, lie within the basal lamina and have multiple processes.

Answer 8

Myoepithelial cells

Question 9

What is the function/role of the myoepithelial cells?

Answer 9

Has contractile properties that facilitate the expelling of salvia into the ductal system.

Question 10

_____ glands have all 3 types of ducts.

Answer 10

Major glands

Question 11

______ glands empty straight into excretory duct.

Answer 11

Minor glands *Never have striated ducts and only sometimes have intercalated

Question 12

T or F, There are many excretory ducts for major salivary glands.

Answer 12

False! There are for MINOR salivary glands.

Question 13

5 descriptive facts about intercalated ducts.

Answer 13

1. Smallest duct
2. Several acini drain into each intercalated duct
3. Ducts are short
4. Cells are cuboidal with a centrally placed nuclei
5. Secrete few proteins
   * Major function is to convey saliva!

Question 14

8 Descriptive facts about Striated ducts.

Answer 14

1. Longer, more active duct
2. Site of resorption of sodium and chloride = turns the salvia (secondary) HYPOTONIC. *requires ATP
3. Secretes Bicarbonate as buffer
4. Columnar cells
5. Highly polarized
6. Short microvilli
7. Prominent mitochondria
8. Numerous infoldings of the basolateral membrane!!!

Question 15

What is the purpose of Excretory/collecting duct?

Answer 15

Carrying salvia to oral cavity * series of connecting ducts that get wider and wider.

Question 16

3. Descriptive facts about Excretory/collecting ducts.

Answer 16

1. No secretion or resorbtion
2. ducts get progressively wider
3. As they get closer to oral cavity epithelium changes from single layer to pseudo stratified, to stratified to keratinized.

Question 17

______ sometimes intermingle with excretory duct cells.

Answer 17

Goblet cells = secrete mucins

Question 18

The sublingual gland is ______ but Primarily ______.

Answer 18

Mixed, but primarily mucous.

Question 19

The submandibular gland is ____, but primarily ______.

Answer 19

Mixed, but primarily serous.

Question 20

Most of the minor salivary glands are _______.

Answer 20

Nearly/pure mucous

Question 21

Von Ebners glands found where?

Answer 21

Posterior of tongue, Foliate and Cirvumvallate papilla.

Question 22

Von Ebners glands are _____ glands

Answer 22

Pure serous (Major lipase secretor)

Question 23

With age general loss of parenchyma can = _____%

Answer 23

30-60% = Does not automatically = dry mouth

Question 24

Hyposalviation is defined as _____.

Question 25

What are some treatments for Hyposalivation?

Answer 25

Artificial saliva
Frequent dental exams
Salivary stimulants (gum, candies)

Question 26

______ can stimulate salivary flow, but their side effects can be prohibitive.

Answer 26

Muscarinic cholinergic agonists