Saliva 1 Flashcards
(48 cards)
What can cause a reduction in salvia?
- head and neck radiotherapy
- autoimmune disease Sjogrens syndrome
- Medications
What does lack of saliva do to the tongue?
Can cause it to become fissured
Salivary function is tested by a technique called _____.
Scintigraphy = Iv injection of isotope or technetium that binds to Na-K-Cl membrane transport system of acinar cells of salivary glands.
What is congenital salivary aplasia?
Missing or underdeveloped salivary glands
True or false, Salivary gland disorders are rare and Genetic in origin.
True
Briefly describe other disorders that can accompany salivary gland agenesis…..
It can occur in isolation or it can be accompanied by other disorders of the ectoderm or 1st brachial arch *such as abnormalities in hair, nails, missing teeth or deafness/
What are the 7 functions of saliva?
- Protection = Mucins (glycoproteins responsible for lubricating mucosal surface and providing protective barrier.
- Buffering = Bicarbonate (buffers acids in mouth)
- Tooth integrity = Proline rich proteins & Statherin (calcium binding proteins contribute to enamel maturation and remineralization)
- Antimicrobial = Lysozyme, peroxidase, defensins, histatins & IgA)
- Tissue repair = Growth Factors
- Digestion = Amylase & Lipase
- Taste = Molecules must dissolve in water to be transported to taste bud.
Salivary glands are classified as a ______ gland.
Exocrine = uses a duct
Normal daytime salivary flow rate = ?
.3-.4ml/min
normal volume of saliva in mouth = ?
0.8-1.1ml
What are the 3 major salivary glands?
Parotid = IX Submandibular = VII Sublingual = VII
What are the minor salivary glands?
Von Ebners gland = IX
Labial
Palatal
Buccal & lingual
_____ Contributes around 60% of salvia.
parotid = whole mouth saliva (watery saliva)
____ contributes around 25% of salvia.
Submandibular
______ contributes around 7-8% of saliva.
submandibular and minor glands
The parotid gland is a ________ gland and the major source of ____P_>
Pure serous = watery saliva *major source of amylase
The Submandibular and sublingual gland are ______ glands.
Mixed serous/mucous glands
Von Ebner’s gland is a ______ gland and the major source of _____.
Pure serous gland. Main source of lipase.
The other minor glands are _____ glands and major source of _____.
Pure serous glands. Major source of Mucins (lubrication)
Where does parotid gland secrete to?
Stensons duct, which opens opposite the 2nd max molar.
Where does submandibular gland secrete?
empties into oral cavity via Whartons duct on the lingual frenum.
Where does the sublingual gland secrete?
empties into a series of ducts on the sublingual fold behind Whartons duct, called the Bartholins and Rivinus’s ducts.
Saliva glands are made up of what 2 division?
Stroma = supporting role (organizing gland into lobes) Parenchyma = does the characteristic work of given gland (makes and secretes salvia)
Stroma is made of _______.
Connective tissue
