S8) The Post-natal Period Flashcards

1
Q

Provide 3 definitions of the post-natal period

A
  • Period from the delivery of the placenta to 6/52 post natal
  • Period when the pregnancy changes revert to the pre-pregnancy state
  • Period of great changes/modifications in lifestyle, psychology, activities, relationships, responsibility, etc.

six weeks after delivery

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2
Q

Describe the hormonal control of growth and development of mammary tissues

A
  • Progesterone, oestrogen, prolactin, GH and adrenal steroids cause hypertrophy in pre-existing alveolar-lobular structures in the breast
  • There is also formation of new alveolae by budding from the milk ducts, with proliferation of milk-collecting ducts
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3
Q

There are high levels of lactogenic hormones (prolactin and hPL) in pregnancy.

Why are only minimal amounts of milk are formed?

A

Oestrogen and progesterone inhibit the effects of lactogenic hormones

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4
Q

How is prolactin released in the post-natal period?

A

Prolactin is released by the action of suckling at a nipple that has become exquisitely sensitive post-delivery

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5
Q

What is the determining factor for milk production?

A

Prolactin levels and milk production are dependent on the frequency and duration of suckling

highest in early puerperium and then slowly reduces

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6
Q

When are prolactin levels at their highest?

A

Prolactin levels are at their highest in the early puerperium and reduce slowly, only returning to normal after weaning

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7
Q

Identify another determining factor for milk secretion

A
  • Milk secretion is also dependent on adequate emptying of the secreting glands
  • Accumulation of milk inside the alveoli will cause distension and atrophy of the glandular epithelium
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8
Q

In 4 steps, describe the hormonal control of the let down reflex

A

⇒ Oxytocin stimulates myoepithelial cells around the alveolae

These cells contract and expel the milk into the milk-collecting ducts

The longitudinal muscle cells in the ducts are stimulated

These cells dilate to improve the free flow of milk towards the nipple ‘let down’ reflex

lobules empty into ductules combining into a duct

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9
Q

Describe the neuroendocrine mechanism controlling the production of milk

A
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10
Q

Describe the neuroendocrine mechanism controlling the secretion of milk

A
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11
Q

What effect does stress have on oxytocin release?

A
  • Maternal stress reduces oxytocin release
  • Increased levels of adrenaline & noradrenaline reduces mammary blood flow, oxytocin release from pituitary and myoepithelial cell contractile response to oxytocin
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12
Q

Describe the anatomical position of the breast

A
  • Breast is located on the anterior thoracic wall and extends horizontally from the lateral border of the sternum to the mid-axillary line
  • It spans between the 2nd and 6th intercostal cartilages and lies superficially to the pectoralis major and serratus anterior muscles
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13
Q

Describe the topography of the breast

A
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14
Q

What is the most prominent gland in the breast?

A

Sebaceous gland

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15
Q

how long after do you have a post natal check up

A

6 weeks after birth

to see if body has gone back to normal

assess feeding of baby, mothers mental and physical health

discuss contraception, breastfeeding, breast, abdominal and pelvic examination

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16
Q

what are some physiological changes

A
  • characterised by low oestrogen levels
  • lower genital tract
  • reaction in vulva, vagina and cervix
  • poor lubrication of the vagina
  • internal os closed
17
Q

when does menstruation return after post partum

A
  • normally after 6 weeks
  • BEFORE:
  • can get heavy bleeding, should not be passing clots though
18
Q

what are the 4 main reasons for PPH

A

Tone (atony)

Tissue (retained placenta)

Thrombin (clotting disorder)

Trauma: Uterus turns inside out, perineal trauma, maternal collapse, sepsis

19
Q

what mental health conditions can arise after giving birth

A
  1. postnatal blues → altered mood
  2. depression → occurs within 4 weeks
  3. puerperal psychosis → occurs within 4 weeks, rare, due to a pre - existing mental illness, anxiety, mania, paranoid thought and delusions
  4. PTSD
20
Q

What is the role of mammogenic hormones

A

promote proliferation of alveolar and duct cells

21
Q

what are the roles of lactogenic hormones

A

promote initiation of milk production

22
Q

what is the role of galactokinetic hormone

A

promote contraction of my-epithelial cells

23
Q

what is the role of gelactopoietic hormone

A

maintain milk production

24
Q

Prolactin

A

PRL is essential for milk production

suckling is a powerful stimulus

25
Q

what is the milk production like

A
  1. initially low and colostrum is produced
  2. contains high fat and immunoglobulin
  3. 800ml a day should be produced
26
Q

how does breastmilk protect baby

A
  1. lactoferrin
  2. populates neonatal gut with non pathogenic flora
  3. bactericidal enzymes
  4. contains specific immunoglobulins
  5. contains lymphocytes
27
Q

what are the components of breast milk

A
  1. lower salt content
  2. higher energy
  3. less protein
  4. more lactose
  5. milk at start has more water
  6. milk at end is higher in fats and iron
28
Q

cessation of lactation

A
  1. is ceases
  2. milk accumulates in alveoli
  3. distension and atrophy of glandular epithelium
  4. local mechanical factors suppress milk secretion
29
Q

why is immunoglobulin A given to baby via great milk important

A
  1. passes into infant gut
  2. can defend itself against endemic environmental pathogen
30
Q

when should you not breast feed

A
  1. HIV
  2. severe maternal illness
  3. mothers on certain meds
31
Q

what are some breast problems that can arise from breastfeeding

A
  1. nipple sensitivity and pain
  2. engorgment
  3. mastitis
  4. breast abscess
  5. breast lump
32
Q

difference between primary and secondary PPH

A
  • primary: loss of 500mls from genital tract within 24 hours of birth
  • secondary: bleeding after 24hrs - 12 weeks after
33
Q

haemostasis

A

blood can pool up in the uterus

34
Q

what is the leading cause for direct maternal death

A

DVT