S3E3 Flashcards
side effects of radiation and chemotherapy
➢ bone marrow suppression
➢ fatigue
➢ GI issues
➢ skin and mucosal issues
➢ pulmonary concerns
➢ cardiovascular effects
➢ Neuro effects
➢ reproductive effects
What type of bone marrow suppression side effects will you see from chemo/radiation?
neutropenic
infection
hemorrhage
thrombocytopenia
What type of fatigue side effects will you see from chemo/radiation?
anemia
toxic substance from treatment
lack of sleep
What type of GI side effects will you see from chemo/radiation?
internal mucosa is sensitive to chemo/radiation
NVD
anorexia
mucositis= decrease in electrolytes and nutrition
What type of skin/mucosa side effects will you see from chemo/radiation?
mouth
oral pharynx
esophagus
What type of pulm side effects will you see from chemo/radiation?
cough
dyspnea
irreversible lung damage
pneumonitis=cough, fever, night sweats, pulm fibrosis
What type of CV side effects will you see from chemo/radiation?
pericarditis
peri effusion
EKG change in LV
What type of Neuro side effects will you see from chemo/radiation?
moments of confusion
memory loss
What type of reproductive side effects will you see from chemo/radiation?
Infertility
What is immunotherapy
- boost or manipulate the immune system to create an environment not conducive for cancer cells to grow
- attack or kill cancer cells directly
Types of immunotherapy
cytokines
vaccines
monoclonal antibodies
Immunotherapy side effects
➢ capillary leak syndrome
➢pulmonary edema
➢bone marrow suppression (less severe compared to chemo)
➢fatigue
➢“flu like syndrome
What is targeted therapy
interferes with cancer growth by targeting specific cell receptors and pathways that are important in tumor growth, they act on specific targets and does less damage to normal cells than chemo. Targeted therapy is personalized treatment based on the biology of the tumor. Expensive
Targeted therapy side effects
Pt can become resistant to targeted therapy, Works best with chemo
➢ capillary leak syndrome
➢pulmonary edema
➢bone marrow suppression (less severe compared to chemo)
➢fatigue
➢“flu like syndrome
What are the 3 goals of cancer treatment
➢Curative
➢Control
➢Palliative
