S2L1 - Drugs only Flashcards

1
Q

Unfractionated heparin

A

Anticoagulant - works on factor Xa and IIa (thrombin)

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2
Q

Protamine

A

a weak base used for UFH reversal to neutralize the weak acid

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3
Q

Fondaparinux

A

HIT type II management

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4
Q

Argatroban

A

A direct thrombin inhibitor to work as an anticoagulant - usually in HIT type II management

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5
Q

Bivalirudin

A

A direct thrombin inhibitor to work as an anticoagulant - usually in HIT type II management

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6
Q

LMWH

A

Anticoagulant - works on Xa only

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7
Q

Tinzaparin

A

a type of LMWH - anticoagulant

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8
Q

Enoxaparin

A

a type of LMWH - anticoagulant

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9
Q

Dalteparin

A

a type of LMWH - anticoagulant

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10
Q

Warfarin

A

An anticoagulant that inhibits the vitamin K dependent synthesis of clotting factors II, VII, IX and X

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11
Q

Dabigatran

A

A novel anticoagulant

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12
Q

Apixaban

A

A novel anticoagulant

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13
Q

Rivaroxaban

A

A novel anticoagulant

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14
Q

PCCs

A

Prothrombin protein concentrate - contain various clotting factors to use when patient is bleed in response to new anti coagulant

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15
Q

Fibrinolytic/thrombolytic drugs

A

Break clots

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16
Q

Streptokinse

A

a fibrinolytic drug

17
Q

tPA

A

AKA alteplase - a fibrinolytic drug - selective clot lysis

18
Q

Reteplase

A

a fibrinolytic drug - selective clot lysis - usually in heart attack

19
Q

Tenecteplase

A

a fibrinolytic drug - selective clot lysis - usually in heart attack

20
Q

Urokinase

A

a fibrinolytic drug from human urine

21
Q

Anistreplase

A

Streptokinase and plasminogen complex to use as a fibrinolytic drug

22
Q

Aspirin

A

An antiplatelet drug to use to irreversibly inhibit COX1 and consequently TXA2 synthesis `

23
Q

ADP antagonists

A

Adenosine diphosphate antagonist - Antiplatelet drug class used as alternative to aspirin - prevents GPIIb/IIIa activation preventing platelet aggregation

24
Q

Ticlopidine

A

Adenosine diphosphate antagonist - Antiplatelet

25
Q

Clopidogrel

A

Adenosine diphosphate antagonist - Antiplatelet

26
Q

Prasugrel

A

Adenosine diphosphate antagonist - Antiplatelet

27
Q

Ticagrelor

A

Adenosine diphosphate antagonist - Antiplatelet

28
Q

Cangrelor

A

Adenosine diphosphate antagonist - Antiplatelet

29
Q

Dipyridamole

A

Weakest anti-platelet that acts as coronary vasodilator to inhibit adenosine uptake

30
Q

Abciximab

A

A glycoprotein IIb/IIIa receptor inhibitor - anti platelet

31
Q

Eptifibatide

A

A glycoprotein IIb/IIIa receptor inhibitor - anti platelet

32
Q

Tirofiban

A

A glycoprotein IIb/IIIa receptor inhibitor - anti platelet