S2_L1: Traumatic Brain Injury Flashcards
Brain injury: Cell death occurs as a result of events that follow after tissue damage
A. Primary injury
B. Secondary injury
C. Both
D. Neither
B. Secondary injury
Brain injury: Treatable and theoretically preventable
A. Primary injury
B. Secondary injury
C. Both
D. Neither
B. Secondary injury
Brain injury: Result from brain tissue coming into contact with an object
A. Primary injury
B. Secondary injury
C. Both
D. Neither
A. Primary injury
Brain injury: Result from brain tissue coming into contact with an external object which can penetrate the bone
A. Primary injury
B. Secondary injury
C. Both
D. Neither
A. Primary injury
Mechanical force causing brain injury: Occurs when the head is prevented from moving after being struck
A. Contact forces
B. Inertial forces
A. Contact forces
Mechanical force causing brain injury: Occurs when the head is set into motion and the brain tissue rapidly accelerates or decelerates
A. Contact forces
B. Inertial forces
B. Inertial forces
Primary Injury: Result from relatively low-velocity impact such as blows (blunt trauma) and ground level falls
A. Diffuse Axonal Injury (DAI)
B. Cerebral / Cortical Contusion
C. Concussion
D. Post Concussional Syndrome
B. Cerebral / Cortical Contusion
Primary Injury: Symptom duration to define persistent deficits range from 3-12 months
A. Diffuse Axonal Injury (DAI)
B. Cerebral / Cortical Contusion
C. Concussion
D. Post Concussional Syndrome
C. Concussion
Primary Injury: Microscopic disruption and tearing of axons and small blood vessels from shear-strain of angular acceleration
A. Diffuse Axonal Injury (DAI)
B. Cerebral / Cortical Contusion
C. Concussion
D. Post Concussional Syndrome
A. Diffuse Axonal Injury (DAI)
Primary Injury: Deceleration and acceleration injury causes shear, tensile,
and compression forces within / to the brain
A. Diffuse Axonal Injury (DAI)
B. Cerebral / Cortical Contusion
C. Concussion
D. Post Concussional Syndrome
A. Diffuse Axonal Injury (DAI)
Primary Injury: Predominant MOI in most individuals with severe to moderate TBI
A. Diffuse Axonal Injury (DAI)
B. Cerebral / Cortical Contusion
C. Concussion
D. Post Concussional Syndrome
A. Diffuse Axonal Injury (DAI)
Primary Injury: Occurs with translation acceleration result in head movement
A. Diffuse Axonal Injury (DAI)
B. Cerebral / Cortical Contusion
C. Concussion
D. Post Concussional Syndrome
B. Cerebral / Cortical Contusion
Primary Injury: Mechanism behind initial loss of consciousness after TBI and results in more generalized deficits (e.g. confusion
and incoordination)
A. Diffuse Axonal Injury (DAI)
B. Cerebral / Cortical Contusion
C. Concussion
D. Post Concussional Syndrome
A. Diffuse Axonal Injury (DAI)
Primary Injury: Elevates the risk for seizures and is more likely to produce focal deficits (e.g. aphasias and motor weakness)
A. Diffuse Axonal Injury (DAI)
B. Cerebral / Cortical Contusion
C. Concussion
D. Post Concussional Syndrome
B. Cerebral / Cortical Contusion
Primary Injury: Headache, agitation, fatigue, irritability, memory deficit, and concentration loss occurring 3 months after the concussion.
A. Diffuse Axonal Injury (DAI)
B. Cerebral / Cortical Contusion
C. Concussion
D. Post Concussional Syndrome
D. Post Concussional Syndrome
Common areas of a contusion are the undersurface of the (1)____ and (2)____ lobes due to the presence of bony prominences on the base of the skull creating brain tissue and vascular
disruption.
- frontal lobe (leads to long term amnesia)
- anterior temporal lobe (leads to short term amnesia)
TRUE OR FALSE: Comatose is a common manifestation of diffuse axonal injury. Recovery from DAI is usually gradual and is commonly
linked to the duration of the coma.
True
Primary Injury: Loss of consciousness d/t direct axonal shearing and
disruption of the intra-axonal cytoskeleton. Then, the axonal disruption leads to swelling.
A. Diffuse Axonal Injury (DAI)
B. Cerebral / Cortical Contusion
C. Concussion
D. Post Concussional Syndrome
A. Diffuse Axonal Injury (DAI)
Primary Injury: Refers to neurons remote from a site of injury, but anatomically connected to the damaged area, becoming functionally depressed
A. Direct Laceration
B. Diaschisis
C. Epidural Hematoma
D. Subdural Hematoma
B. Diaschisis
Primary Injury: Focal cortical lesions that can affect contralateral cortical functioning by way of interconnections in the corpus callosum
A. Direct Laceration
B. Diaschisis
C. Epidural Hematoma
D. Subdural Hematoma
B. Diaschisis
Primary Injury: Local impact and subsequent laceration of underlying
dural veins and arteries
A. Direct Laceration
B. Diaschisis
C. Epidural Hematoma
D. Subdural Hematoma
C. Epidural Hematoma
Note: It’s usually associated to a damaged artery
Primary Injury: Caused by inertial forces and the tearing of bridging
veins
A. Direct Laceration
B. Diaschisis
C. Epidural Hematoma
D. Subdural Hematoma
D. Subdural Hematoma
Primary Injury: Neurologic emergency
because of its quick expansion and rapidly causing neurological degeneration
A. Direct Laceration
B. Diaschisis
C. Epidural Hematoma
D. Subdural Hematoma
C. Epidural Hematoma
Primary Injury: Caused by metallic or bony fragments that can be brought about by significant blunt trauma, penetrating injury, depressed skull fracture, or gunshot or other missile injury
A. Direct Laceration
B. Diaschisis
C. Epidural Hematoma
D. Subdural Hematoma
A. Direct Laceration
Genetic disorders related to inadequate lipid metabolism, where fatty cells deposit in organs like liver & spleen. These progress to loss of function of the nerves and brain.
Gaucher’s / Niemann-Pick
Non-traumatic brain injury: Toxic exposure to
- Manganese
- Zinc
- Copper
A. Wilson’s disease
B. Parkinson’s disease
C. Multiple sclerosis
- B
- C
- A
2nd leading cause of TBI
Motor vehicle/traffic accidents
Leading cause of TBI
Falls
AAN Concussion Grading Scale: Concussion symptoms or mental status changes resolve in less than 5 min
A. Grade 1
B. Grade 2
C. Grade 3
A. Grade 1
AAN Concussion Grading Scale: Concussion symptoms or mental status change lasts longer than 15 min
A. Grade 1
B. Grade 2
C. Grade 3
B. Grade 2
AAN Concussion Grading Scale: Loss of
consciousness (brief or prolonged)
A. Grade 1
B. Grade 2
C. Grade 3
C. Grade 3
Enumerate the key criteria of a concussion
Pt experiences at least one of the following:
1. Confusion
2. Disorientation
3. Loss of consciousness for less than 30 mins
4. Post-Traumatic Amnesia (PTA) for less than 24 hours
5. Other transient focal neurologic abnormalities
Pt has a GCS score of 13-15 after 30 minutes or
presentation to a healthcare facility
Assesses 18 domains of function for children of ages 0-7
A. Disability Rating Scale
B. Functional Independence Measure
C. WeeFIM
D. 6-minute walk test
C. WeeFIM
An observer-rated, 30-point, 30-point continuous scale that provides quantitative information to document the progress of patients with severe head injury from coma to community
reintegration.
A. Disability Rating Scale
B. Functional Independence Measure
C. WeeFIM
D. 6-minute walk test
A. Disability Rating Scale
Note: The higher the score, the more disabled
Secondary Injury: Lack of oxygenated blood flow to the brain tissue that may cause severe damage to parenchymal tissues
A. Increased Intracranial Pressure
B. Brain Infection
C. Hemorrhage
D. Hypoxic - Ischemic Injury
D. Hypoxic - Ischemic Injury
Secondary Injury: Caused by systemic hypotension, anoxia, or damage to specific vascular territories of the brain
A. Increased Intracranial Pressure
B. Brain Infection
C. Hemorrhage
D. Hypoxic - Ischemic Injury
D. Hypoxic - Ischemic Injury
Secondary Injury: This leads to a decrease in the cerebral perfusion pressure and it can cause herniations of the tonsillar part of the brain.
A. Increased Intracranial Pressure
B. Brain Infection
C. Hemorrhage
D. Hypoxic - Ischemic Injury
A. Increased Intracranial Pressure
A major problem for active combat military personnel due to frequent use of explosives in the battlefront. This particular MOI is very important to ask in patients whose occupation involved military or police services.
Blast Injury
Enumerate the components of the Cushing’s Triad
Bradycardia
Hypertension
Irregular breathing
Normal Intracranial Pressure (ICP)
5-20 cm of H2O (Accd to Sullivan)
Normal Cerebral Perfusion Pressure (CPP)
50-70 mmHg
Ancillary Procedure: Bone lesions/fractures
A. Skull X-ray
B. Ventriculography
C. Computerized Tomography Scan
D. Magnetic Resonance Imaging
E. Positron Emission Tomography
A. Skull X-ray
Ancillary Procedure: Tumors, increase in ICP
A. Skull X-ray
B. Ventriculography
C. Computerized Tomography Scan
D. Magnetic Resonance Imaging
E. Positron Emission Tomography
B. Ventriculography
Ancillary Procedure: Primary method in examining tumors
and vascular abnormalities, blood flow
A. Skull X-ray
B. Ventriculography
C. Computerized Tomography Scan
D. Magnetic Resonance Imaging
E. Positron Emission Tomography
D. Magnetic Resonance Imaging
Ancillary Procedure: Calcifications, hemorrhage, cerebral edema, cerebral infarction, tumor
A. Skull X-ray
B. Ventriculography
C. Computerized Tomography Scan
D. Magnetic Resonance Imaging
E. Positron Emission Tomography
C. Computerized Tomography Scan
Ancillary Procedure: Imaging for cerebral blood flow and brain metabolism
A. Skull X-ray
B. Ventriculography
C. Computerized Tomography Scan
D. Magnetic Resonance Imaging
E. Positron Emission Tomography
E. Positron Emission Tomography
Cerebral edema occurs within ___ after vascular occlusion
30 mins
Assesses the participation restriction domain of ICF
A. Disability Rating Scale
B. Functional Independence Measure
C. WeeFIM
D. 6-minute walk test
A. Disability Rating Scale
Blast Injury: May be brought about by shrapnel or other objects hurled to the individual e.g. blunt or
penetrating traumas
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
B. Secondary injury
Blast Injury: victim is flung backward and
hits an object (wall / ground)
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
C. Tertiary injury
Blast Injury: Occurs as a concomitant closed injury brought about by asphaxia (lack of oxygen), and exposure to toxic inhalants
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
D. Quarternary injury
Blast Injury: Direct effect of blast overpressure, direct blast wave propagation transcranially
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
A. Primary injury
Blast Injury: Fragmentation injuries
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
B. Secondary injury
Blast Injury: Open or closed brain injuries
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
C. Tertiary injury
Blast Injury: Effects of structural collapse and of persons being
thrown by the blast wind
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
C. Tertiary injury
Blast Injury: Leads to concussion
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
A. Primary injury
Blast Injury: Leads to rupture of tympanic membranes
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
A. Primary injury
Blast Injury: Leads to subdural hematoma and diffuse axonal injury
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
A. Primary injury
Blast Injury: Transfer of blast energy to the blood vessels trigger oscillations going to the brain, thus
increasing CSF or venous pressure.
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
A. Primary injury
Additional: The elevations in CSF or increased venous
pressure may be due to the compression of
thorax and abdomen brought about by the blast wave propagation through the blood vessels or CSF.
Blast Injury: Examples are eardrum rupture and lung injury
A. Primary injury
B. Secondary injury
C. Tertiary injury
D. Quarternary injury
A. Primary injury
Glasgow Outcome Scale (Extended) Category: Needs full assistance in ADL throughout the
day
A. Dead
B. Vegetative State
C. Lower Severe Disability
D. Upper Severe Disability
C. Lower Severe Disability
Glasgow Outcome Scale (Extended) Category: Needs some supervision / assistance in ADL but can be alone for >8h/d
A. Dead
B. Vegetative State
C. Lower Severe Disability
D. Upper Severe Disability
D. Upper Severe Disability
Glasgow Outcome Scale (Extended) Category: No cerebral cortical function that can be
judged by behavior; Not able to follow simple commands or communicate
A. Dead
B. Vegetative State
C. Lower Severe Disability
D. Upper Severe Disability
B. Vegetative State