S2) Mitosis and Meiosis Flashcards
Identify all the stages in the cell cycle
- G1
- S Phase
- G2 Phase
- M Phase
Describe what happens the G1 phase and when it begins
- Begins immediately after mitosis
- Synthesis of RNA, proteins, and organelles
Describe what occurs in the S Phase
DNA replication occurs, i.e. chromosomes form sister chromatids
Describe what occurs in the G2 Phase
- Mitochondria divide
- Synthesis of precursors of spindle fibres
Identify all the stages of M Phase (mitosis)
- Prophase
- Prometaphase
- Metaphase
- Anaphase
- Telophase
What occurs in prophase?
- Chromatin condenses due to supercoiling and chromosomes become visible
- Nucleoli disappear
- Nuclear envelope breaks down
- Centrioles divide and migrate to opposite poles
What occurs in prometaphase?
- Microtubules produce spindle fibres form
- Spindle fibres attach to centromere of chromosomes
What occurs in metaphase?
Chromosomes, with spindle fibres attached, line up on the equator of the dividing cell
What occurs in anaphase?
- Centromeres divide, converting each sister chromatid into a chromosome
- Chromosomes migrate toward opposite ends of the cell until there is a complete set of chromosomes at each end of the cell
What occurs in telophase?
- Chromosomes reach the opposite poles of the cell
- Chromatin decondenses & spindle fibres break down
- Nuclear membrane reforms
- Nucleoli reappear
What occurs in cytokinesis?
- Cleavage furrow forms at equator of cell and deepens
- Cytoplasm divides
- New nuclear envelope forms
Describe the structure of chromosomes
- Each chromatid consist of one identical DNA molecule
- Each chromatid has a p (short) and q (long) arm
- Telomeres at the end of each chromatid
- Centromeres link sister chromatids
Identify the different types of chromosome structures
What occurs in meiosis?
- Members of a chromosome pair separate from each other
- Each daughter cell receives a haploid (n) set of 23 chromosomes
- These haploid cells form gametes (sperm and egg)
Explain the reduction that occurs in meiosis
- Before cells enter meiosis, the chromosomes replicate during interphase
- Meiosis I reduces the chromosome number accomplished by two rounds of division (meiosis I and meiosis II)
How does fertilisation affect the overall chromosome number?
- Fusion of two haploid gametes in fertilisation restores the chromosome number to the diploid number of 46
- Fertilised egg has a full set of genetic information
Explain what is meant by the following terms:
- Homologous chromosomes
- Sister chromatids
- Non-sister chromatids
- Homologous chromosomes have the identical DNA but may have different alleles
- Sister chromatids have identical DNA and the same alleles
- Non-sister chromatids have identical DNA, but may have different alleles