?s Miller said he would ask (Quiz 3)

Question 1

Optimal T4:T3 ratio

Answer 1

4:1

T4: much longer half life and we depend on the breakdown of T4 into T3

Question 2

How is Synthroid dosed vs. Armour thyroid?

Answer 2

Synthroid: mcg
Armour: mg

Question 3

Long term elevation of serum T3 may accelerate what disease processes?

Answer 3

Cardiac disease

Osteoperosis

Question 4

If a pt has Addison’s and hypothyroidism what do you need to take into consideration?

Answer 4

If you start thyroid replacement without first replacing cortisol it can be fatal.

Question 5

60 mg of Thyroid USP is equal to what dosage of Synthroid? to Cytomel?

Answer 5

60 mg Thyroid USP (Armour) = 100 mcg of Synthroid (T4) = 25 mcg of Cytomel (T3)

Question 6

How is Hyperthyroidism diagnoses via lab values?

Answer 6

High TSH with low T3/T4

Question 7

What drug has a minimal effect of blocking peripheral conversion of T4 to T3?

Answer 7

Methimazole/Tapazole

Propylthiouracil (PTU) has a notable effect.

Question 8

Super physiological doses of iodine has what effect?

Answer 8

Stuns the thyroid and stops the production of thyroid hormone.