RULES OF INHERITANCE - NON - MENDELIAN

Question 1

Any pattern of inheritance in which traits do not segregate according to Mendel’s laws

Answer 1

non-mendelian genetics

Question 2

Describes the inheritance of traits linked to single genes on chromosome in nucleus

Answer 2

non-mendelian genetics

Question 3

these are conditions affected by several loci

Answer 3

non-mendelian genetics

Question 4

A condition when during the heterozygous condition the dominant allele does not completely overpower the recessive allele but has blending of trait

Answer 4

incomplete dominance

Question 5

A condition when during the heterozygous condition the dominant allele does not completely overpower the recessive allele and has no blending of trait

Answer 5

codominance

Question 6

Dominant allele only partially mask the presence of recessive trait

Answer 6

incomplete dominance

Question 7

Neither allele is dominant or recessive

Answer 7

codominance

Question 8

these genes does not produce any antigen on the RBC

Answer 8

amorph/silent gene

Question 9

what are the genotypes of blood type A?

Answer 9

AA or AO

Question 10

what are the genotypes of blood type B?

Answer 10

BB or BO

Question 11

what are the genotypes of blood type AB?

Answer 11

A B

Question 12

what are the genotypes of blood type O?

Answer 12

OO

Question 13

Inheritance pattern for traits that are controlled by more than one gene

Answer 13

polygenic inheritance

Question 14

there is a phenotype gradient in this kind of inheritance

Answer 14

polygenic inheritance

Question 15

Multiple genes affects the inheritance of one trait

Answer 15

polygenic inheritance

Question 16

Genes capable of causing death of organism carrying them

Answer 16

lethal genes

Question 17

The effect on phenotype is profoundly negative and causes the organism to exhibit many disadvantageous characteristics which can lead to death

Answer 17

lethal genes

Question 18

Death from genetic disease can occur at any stage of development or life.

Answer 18

lethal genes

Question 19

this disease is caused by an imitation in the enzyme hexosaminidase-Ab having a buildup of fatty acid in the cell and limit the life span to 3-5 years

Answer 19

tay-sachs disease

Question 20

this disease is characterized with progressive breakdown of nerve cell in the brain and limits the life span from 10-25 years only

Answer 20

huntington’s disease

Question 21

if two people with achondroplasia have children, each child has how many chances of inheriting achondroplasia?

Answer 21

2/3

Question 22

if two people with achondroplasia have children, each child has how many chances of having a normal height?

Answer 22

1/3

Question 23

if two people with achondroplasia have children, each child has how many chance of dying as embryos?

Answer 23

1/4

Question 24

if one person with achondroplasia had a children with a normal person how many chances does each child inherits achondroplasia?

Answer 24

1/2

Question 25

if one person with achondroplasia had a children with a normal person how many chances does each child have a normal height?

Answer 25

1/2

Question 26

These charts are used to display family relationships and depict which relatives have specific phenotypes and sometimes genotypes

Answer 26

pedigrees

Question 27

Represents relationship and sometimes traits

Answer 27

pedigrees

Question 28

Interaction between alleles in heterozygotes

Answer 28

patterns of inheritance

Question 29

- one allele controls the phenotype - one parent must have the trait - does not skip generation

Answer 29

dominant

Question 30

- does not control the phenotype - not expressed in heterozygous - neither parent is required to have the trait since they can be heterozygous

Answer 30

recessive

Question 31

what is the exception in recessive allele for it to be expressed even in heterozygotes?

Answer 31

sex-link inheritance (x-link or y-link)

Question 32

the gene in question is located on one of the numbered chromosome or non-sex chromosome

Answer 32

autosomal

Question 33

what is the ratio of autosomal inheritance between men and women

Answer 33

50/50

Question 34

Transmission of traits depends on the genes in sex chromosome

Answer 34

x-linked/sex-linked

Question 35

what transmission is not observed in sex-link inheritance?

Answer 35

male-to-male transmission

Question 36

One mutated copy of the gene in each cell is sufficient for a person to be affected

Answer 36

autosomal dominant

Question 37

male & female can transmit the trait to their offspring and does not skip generation

Answer 37

autosomal dominant

Question 38

both parents are affected and homozygote for dominant condition is severe

Answer 38

autosomal dominant

Question 39

Need 2 mutated copies of gene for it to manifest

Answer 39

autosomal recessive

Question 40

affected person can have unaffected parents (carrier)

Answer 40

autosomal recessive

Question 41

in autosomal recessive, if you have heterozygous parents, what is the ratio of the progeny that will be affected?

Answer 41

1/4

Question 42

this show fewer affected individual and skips generation

Answer 42

autosomal recessive

Question 43

what type of inheritance is involved in huntington disease?

Answer 43

autosomal dominant

Question 44

what type of inheritance is involved in neurofibromatosis?

Answer 44

autosomal dominant

Question 45

what type of inheritance is involved in cystic fibrosis?

Answer 45

autosomal recessive

Question 46

what type of inheritance is involved in albinism?

Answer 46

autosomal recessive

Question 47

there is no male to male transmission and it is more common in female

Answer 47

x-linked dominant

Question 48

in x-linked dominant, if the father is affected, which offspring will inherit the gene?

Answer 48

daughters only

Question 49

in x-linked dominant, if the mother is affected, which offspring will inherit the gene?

Answer 49

son and daughter

Question 50

this has severe effect in male because there is no other allele to mask its effects

Answer 50

x-linked dominant

Question 51

this always manifests in males but is rarely expressed in heterozygous female; skipping of generation

Answer 51

x-linked recessive

Question 52

affected sons are born to affected mother

Answer 52

x-linked recessive

Question 53

there is no male-male transmission but all daughters of affected father will become carrier

Answer 53

x-linked recessive

Question 54

what type of inheritance is involved in hemophilia A?

Answer 54

x-linked recessive

Question 55

what type of inheritance is involved in G6PD?

Answer 55

x-linked recessive

Question 56

this is also called as holandric inheritance and only males are affected

Answer 56

y-linked recessive

Question 57

it is passed from father to all sons and does not skip generations

Answer 57

y-linked recessive

Question 58

Mutations in mitochondrial DNA

Answer 58

mitochondrial inheritance

Question 59

Inherited through the maternal line

Answer 59

mitochondrial inheritance

Question 60

Only daughters can pass it to their children but can affect both male and female offspring

Answer 60

mitochondrial inheritance