RTI Treatment Flashcards
DOC for GAS pharyngitis_____?
Penicillin V
Alternative Agents for GAS pharyngitis
Amoxicillin Penicillin G benzathine Macrolide (penicillin-allergic patients)--Azythromycin Clindamycin 1st and 2nd Generation Cephalosporin
DOC for Bacterial Sinusitis
Amoxicillin
Alternative Agents for Bacterial Sinusitis
Amoxicillin-clavulanic acid
Macrolide (penicillin-allergic patients)
Co-trimoxazole
2nd or 3rd generation cephalosporin
DOC for Bacterial otitis media
Amoxicillin
Alternative agents for Bacterial otitis media
Amoxicillin-clavulanic acid
Macrolide (penicillin-allergic pts)–Azythromycin
Clindomycin
2nd or 3rd generation cephalosporin
Empirical Treatment for Outpatient CAP (no comorbidities)
Macrolide or Doxycycline
no antimicrobials within the last 3 months
Empirical Treatment for Outpatient CAP with comorbidities
Respiratory Fluoroquinolone or B-lactam plus a macrolide
Immunosuppressing conditions or use of immunosuppressing drugs; use of antimicrobials within previous 3 months
Empirical Therapy for Inpatient CAP (Non ICU)
Respiratory Fluoroquinolone or B-lactam plus a macrolide
Empirical Therapy for Inpatient CAP (ICU)
B-lactam plus either azithromycin or respiratory fluoroquinolone
For penicillin-allergic patients: resp. Fluoroquinolone plus aztreonam
Aspiration Pneumonia (anaerobes)
DOC: Clindamycin
2nd line Metronidazole
Bordetella pertussis
DOC: Macrolide
2nd line: Cotrimoxazole
Chlamydia pneumonia
DOC: Macrolide, doxycycline
Haemophillus influenzae (otitis media, sinusitis)
Non-B-lactamase producing
DOC: Amoxicillin
2nd line: 2nd or 3rd generation cephalosporin, cotrimoxazole
Haemophillus influenzae (otitis media, sinusitis)
B-lactamase producing
DOC: 2nd or 3rd generation cephalosporin, amoxicillin-clavulanic acid
2nd line: Co-trimoxazole
Klebsiella pneumonia
DOC: Ceftriaxone, cefotazime
2nd line: Fluoroquinolones
Legionella sp.
DOC: Fluoroquinolones, azithromycin
2nd line: Doxycycline, cotrimoxazole
Moraxella catarrhalis
DOC: Amoxicillin-clavulanic acid, 2nd or 3rd generation cephalosporins, co-trimoxazole
2nd line: Macrolide
Mycoplasma Pneumoniae
DOC: Macrolide, doxycycline
2nd line: 3rd or 4th generation fluoroquinolone
Pseudomonas Aeruginosa
DOC: Antipseudomonal penicllin (pipercillin or tigercillin), ciprofloxacin
2nd line: levofloxacin, aztreonam, aminoglycoside
Staphylococcus aureus (Methicillin susceptible)
DOC: Antistaphylococcal penicllin (Naphcillin, oxicillin)
2nd line: 2nd or 3rd generations cephalosporin, clindamycin, fluoroquinolone, imipenem
Staphylococcus aureus (Methicillin resistant)
DOC: Vancomycin, linezolid
2nd line: Ceftaroline (5th generation cephalosporin)
Streptococcus pneumoniae
Penicillin non-resistant
DOC: Penicillin G, amoxicillin
2nd line: Cephalosporin, clindamycin, fluoroquinolone, macrolide, cotrimoxazole
Streptococcus pneumoniae (Penicillin resistant)
DOC: depends on susceptibility; includes 2nd and 3rd generation of cephalosporins, 3rd and 4th generation fluoroquinolones
2nd line: Vancomycin, linezolid, streptogramins
Tularemia
DOC: Streptomycin
2nd line: Gentamicin, chloramphenicol
