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Pharmacology Term 4 > Drug Reactions > Flashcards

Drug Reactions Flashcards

Which drugs are known to cause?

1
Q

Which drugs cause Coronary Vasospam?

A

CASE

Cocaine, Amphetamines, Sumatriptan, Ergot Alkaloids

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2
Q

Which drugs cause Cutaneous Flushing?

A

Flushed from VANCEN

Vancomycin, Adenosine, Niacin, Ca2+ channel blockers, Echinocandins, Nitrates

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3
Q

Which drugs cause Dilated Cardiomyopathy? How do you prevent this?

A

Anthracyclines: doxorubicin and daunorubicin

Prevent using Dexrazoxane

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4
Q

Which drugs cause torades de pointes?

A

Prolonged QT intervals:

ABCDE

AntiArrhythmics (Class IA and III), antiBiotics (macrolides), Anti (C)psychotics (haloperidol), antiDepressants (TCAs), AntiEmetics (ondansetron)

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5
Q

Which drugs cause Fanconi Syndrome?

A

Cisplatin, ifosfamide, expired tetracyclines, tenofovir,

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6
Q

Which drugs cause Hemorrhagic cystitis?

A

Cyclophosphamide, ifosfamide

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7
Q

Which drugs cause interstitial nephritis? (8)

A

Penicillins, ciprofloxacin , cephalosporins, macrolides, furosemide, NSAIDS, PPIs, sulfa drugs

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8
Q

What drugs cause ATN?

A

aminoglycosides, heavy metals (lead), myoglobinurina (from crush injury), radiocontrast dye, urate

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9
Q

What drugs cause Renal Papillary necrosis?

A

Chronic analegesic abuse: phenacetin or aspirin

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10
Q

What drugs cause a dry cough?

A

ACE Inhibitors

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11
Q

Which drugs cause Pulmonary Fibrosis?

A

Methotrexate, Nitrofurantoin, Carmustine, Bleomycin, Busulfan, Amiodarone

My Nose Cannot Breathe Bad Air

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12
Q

Which drugs cause agranulocytosis?

A

Clozapine, Carbamazepine, Propylthiouracil, Methimazole, Colchicine, Ganciclovir

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13
Q

Which drugs cause Aplastic Anemia?

A

Carbamazepine, Methimazole, NSAIDS, Benzene, Chlorophenicol, Propylthiouracil

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14
Q

Which drugs cause Direct Coombs-positive hemolytic anemia?

A

Penicillin, methyldopa, Cephalosporins

P Diddy Coombs

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15
Q

Which drugs cause reaction with eosinophilia and systemic symptoms?

A

Allopurinol, anticonvulsants, antibiotics, sulfa drugs

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16
Q

Which drugs cause Gray Baby Syndrome?

A

Chloramphenicol

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17
Q

Which drugs cause hemolysis in G6PD deficiency?

A

Isoniazid, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin

hemolysis IS D PAIN

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18
Q

Which drugs cause Megaloblastic Anemia?

A

Hydroxyurea, Phenytoin, Methotrexate, Sulfa drugs

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19
Q

Which drugs cause Thrombocytopenia?

A

Heparin, Vancomycin, Linezolid

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20
Q

Which drugs cause Thrombotic complications?

A

Combined oral contraceptives, hormone replacement therapy, SERMs (tamoxfen, raloxifene, clomiphene)

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21
Q

Which drugs cause acute cholestatic hepatitis jaundice?

A

Macrolides (erythromicin)

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22
Q

Which drugs cause diarrhea?

A

Acamprosate, antidiabetic agents (acarbose, metformin, pramlintide), colchicine, cholinesterase inhibitors, lipid lowering agents (ezetimibe, orlistat), macrolides, quinidine, SSRIs

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23
Q

Which drugs cause focal to massive hepatic necrosis?

A

Halothane, Amanita phalloides (Death cap mushrooms), valproic acid, acetaminophen

Liver “HAVAc”

24
Q

Which drugs cause hepatitis?

A

Rifampin, isoniazid pyrazinamide, statins, fibrates

25
Which drugs cause pancreatitis?
Didanosine, Corticosteroids, alcohol, valproic acid, azathioprine, diuretics (furosemide, HCTZ) Drugs Causing A Violent Abdominal Distress
26
Which drugs cause pill-induced esophagitis? And how do you alleviate it?
Bisphosphantes, ferrous sulfate, NSAIDs, potassium chloride, tetracyclines **Minimized with upright posture and adequate water ingestion
27
Which drugs cause Pseudomembranous colitis?
Ampicillin, cephalosporins (esp ceftiaxone), clindamycin, fluoroquinolones
28
Which drugs can cause asthma-like attacks?
Aspirin (increased leukotrienes), tartrazine (food-coloring), B-adrenergic agonists, sulfating agents
29
Which drugs cause adrenocortical insufficiency?
HPA suppression secondary to glucocorticoid withdrawal
30
Which drugs cause diabetes insipidus?
Lithium, demeclocycline
31
Which drugs cause hot flashes?
SERMs (tamoxifen, clomiphene, raloxifene
32
Which drugs cause hyperglycemia?
Tacrolimus, Protease inhibitors, Niacin, HCTZ, Corticosteroids The People Need Hard Candies
33
Which drugs cause hyperprolactinemia?
Typical antipsychotics (haloperidol), atypical antipsychotics (quetipine), metoclopromide, methyldopa
34
Which drugs cause hyperthyroidism?
Lithium, amiodarone
35
Which drugs cause Hypothyroidism?
Amiodarone, sulfanoamides, Lithium I am suddenly Lethargic
36
Which drugs cause SIADH?
Carbamazepine, Cyclophosohamide, SSRIs Cant Concentrate Serum Sodium
37
Which drugs cause drug-induced lupus?
Methyldopa, sulfa drugs, hydralazine, isoniazid, procainamide, phenytoin, etanercept Having Lupus is Mega SHIPP-E
38
Which drugs cause fat redistribution?
Protease Inhibitors, Glucocorticoids Fat PiG
39
Which drugs cause gingival hyperplasia?
Cyclosporine, Ca2+ channel blockers, Phenytoin
40
Which drugs cause Hyperuriciemia (gout)?
Pyrazindamide,Thiazides, Furosemide, Niacin, Cyclosporine
41
Which drugs cause Osteoporosis?
Corticosteroids, depot medroxyprogesterone acetate, GnRH agonists, aromatse inhibitors, anticonvulsants, heparin, PPIs
42
Which drugs cause myopathy?
Statins, fibrates, niacin, colchicine, daptomycin, hydroxychloroquine, interferon-A, penicillamine, glucocorticoids
43
Which drugs cause photosensitivity?
Sulfonamides, amiodarone, Tetracyclines, 5-FU
44
Which drugs cause Rash (Steven-Johnson Syndrome)?
Anti-epileptic drugs (lamogtigone), allopurinol, sulfa drugs, penicillin
45
Which drugs cause teeth discoloration?
Tetracyclines
46
Which drugs cause tendon and cartilage damage?
Fluoroquinolones
47
Which drugs cause Cinchonism?
Quinidine, Quinine
48
Which drugs present with Parkinson-like Syndrome?
Antipsychotics, Resperipine, Metoclopromide Cogwheel Rigidity of the ARM
49
Which drugs cause peripheral neuropathy?
Phenytoin, Vincristine
50
Which drugs cause Pseudotumor cerebri?
Growth hormones, tetracyclines, Vitamin A
51
Which drugs cause seizures?
Isoniazid, (Vitamin B6 deficiency), Bupropion, Imipenem/cilastatin, Tramadol, Enflurane BIITE my tongue during seizures
52
Which drugs cause Tardive Dyskinesia?
Antipsychotics, metoclopromide
53
Which drugs cause visual disturbance?
Topiramate (diplopia/blurred vision), Digoxin (yellow-tinged), isoniazid (optic neuropathy/ color vision changes), Vigabatrin (bilateral visual field defects), PDE-5 inhibitors (blue-tinged vision), Ethambutol These Drugs Irritate Very Precious Eyes
54
Which drugs cause antimuscarinic effects?
Atropine, TCAs, H1-blockers, antipsychotics
55
Which drugs cause disulfiram-like reactions?
1st generation Sulfonylureas, Procarbazine, certain Cephalosporins, Griseofulvin, Metronidazole
56
Which drugs cause nephrotoxicity/ototoxicity?
Loop diuretics, Aminoglycosides, cisplatin, Vancomycin, amphotericin B

Pharmacology Term 4 (3 decks)

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