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Pharmacology Term 4 > Drug Reactions > Flashcards

Drug Reactions Flashcards

Which drugs are known to cause?

1
Q

Which drugs cause Coronary Vasospam?

A

CASE

Cocaine, Amphetamines, Sumatriptan, Ergot Alkaloids

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2
Q

Which drugs cause Cutaneous Flushing?

A

Flushed from VANCEN

Vancomycin, Adenosine, Niacin, Ca2+ channel blockers, Echinocandins, Nitrates

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3
Q

Which drugs cause Dilated Cardiomyopathy? How do you prevent this?

A

Anthracyclines: doxorubicin and daunorubicin

Prevent using Dexrazoxane

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4
Q

Which drugs cause torades de pointes?

A

Prolonged QT intervals:

ABCDE

AntiArrhythmics (Class IA and III), antiBiotics (macrolides), Anti (C)psychotics (haloperidol), antiDepressants (TCAs), AntiEmetics (ondansetron)

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5
Q

Which drugs cause Fanconi Syndrome?

A

Cisplatin, ifosfamide, expired tetracyclines, tenofovir,

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6
Q

Which drugs cause Hemorrhagic cystitis?

A

Cyclophosphamide, ifosfamide

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7
Q

Which drugs cause interstitial nephritis? (8)

A

Penicillins, ciprofloxacin , cephalosporins, macrolides, furosemide, NSAIDS, PPIs, sulfa drugs

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8
Q

What drugs cause ATN?

A

aminoglycosides, heavy metals (lead), myoglobinurina (from crush injury), radiocontrast dye, urate

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9
Q

What drugs cause Renal Papillary necrosis?

A

Chronic analegesic abuse: phenacetin or aspirin

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10
Q

What drugs cause a dry cough?

A

ACE Inhibitors

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11
Q

Which drugs cause Pulmonary Fibrosis?

A

Methotrexate, Nitrofurantoin, Carmustine, Bleomycin, Busulfan, Amiodarone

My Nose Cannot Breathe Bad Air

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12
Q

Which drugs cause agranulocytosis?

A

Clozapine, Carbamazepine, Propylthiouracil, Methimazole, Colchicine, Ganciclovir

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13
Q

Which drugs cause Aplastic Anemia?

A

Carbamazepine, Methimazole, NSAIDS, Benzene, Chlorophenicol, Propylthiouracil

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14
Q

Which drugs cause Direct Coombs-positive hemolytic anemia?

A

Penicillin, methyldopa, Cephalosporins

P Diddy Coombs

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15
Q

Which drugs cause reaction with eosinophilia and systemic symptoms?

A

Allopurinol, anticonvulsants, antibiotics, sulfa drugs

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16
Q

Which drugs cause Gray Baby Syndrome?

A

Chloramphenicol

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17
Q

Which drugs cause hemolysis in G6PD deficiency?

A

Isoniazid, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin

hemolysis IS D PAIN

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18
Q

Which drugs cause Megaloblastic Anemia?

A

Hydroxyurea, Phenytoin, Methotrexate, Sulfa drugs

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19
Q

Which drugs cause Thrombocytopenia?

A

Heparin, Vancomycin, Linezolid

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20
Q

Which drugs cause Thrombotic complications?

A

Combined oral contraceptives, hormone replacement therapy, SERMs (tamoxfen, raloxifene, clomiphene)

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21
Q

Which drugs cause acute cholestatic hepatitis jaundice?

A

Macrolides (erythromicin)

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22
Q

Which drugs cause diarrhea?

A

Acamprosate, antidiabetic agents (acarbose, metformin, pramlintide), colchicine, cholinesterase inhibitors, lipid lowering agents (ezetimibe, orlistat), macrolides, quinidine, SSRIs

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23
Q

Which drugs cause focal to massive hepatic necrosis?

A

Halothane, Amanita phalloides (Death cap mushrooms), valproic acid, acetaminophen

Liver “HAVAc”

24
Q

Which drugs cause hepatitis?

A

Rifampin, isoniazid pyrazinamide, statins, fibrates

25
Q

Which drugs cause pancreatitis?

A

Didanosine, Corticosteroids, alcohol, valproic acid, azathioprine, diuretics (furosemide, HCTZ)

Drugs Causing A Violent Abdominal Distress

26
Q

Which drugs cause pill-induced esophagitis?

And how do you alleviate it?

A

Bisphosphantes, ferrous sulfate, NSAIDs, potassium chloride, tetracyclines

**Minimized with upright posture and adequate water ingestion

27
Q

Which drugs cause Pseudomembranous colitis?

A

Ampicillin, cephalosporins (esp ceftiaxone), clindamycin, fluoroquinolones

28
Q

Which drugs can cause asthma-like attacks?

A

Aspirin (increased leukotrienes), tartrazine (food-coloring), B-adrenergic agonists, sulfating agents

29
Q

Which drugs cause adrenocortical insufficiency?

A

HPA suppression secondary to glucocorticoid withdrawal

30
Q

Which drugs cause diabetes insipidus?

A

Lithium, demeclocycline

31
Q

Which drugs cause hot flashes?

A

SERMs (tamoxifen, clomiphene, raloxifene

32
Q

Which drugs cause hyperglycemia?

A

Tacrolimus, Protease inhibitors, Niacin, HCTZ, Corticosteroids

The People Need Hard Candies

33
Q

Which drugs cause hyperprolactinemia?

A

Typical antipsychotics (haloperidol), atypical antipsychotics (quetipine), metoclopromide, methyldopa

34
Q

Which drugs cause hyperthyroidism?

A

Lithium, amiodarone

35
Q

Which drugs cause Hypothyroidism?

A

Amiodarone, sulfanoamides, Lithium

I am suddenly Lethargic

36
Q

Which drugs cause SIADH?

A

Carbamazepine, Cyclophosohamide, SSRIs

Cant Concentrate Serum Sodium

37
Q

Which drugs cause drug-induced lupus?

A

Methyldopa, sulfa drugs, hydralazine, isoniazid, procainamide, phenytoin, etanercept

Having Lupus is Mega SHIPP-E

38
Q

Which drugs cause fat redistribution?

A

Protease Inhibitors, Glucocorticoids

Fat PiG

39
Q

Which drugs cause gingival hyperplasia?

A

Cyclosporine, Ca2+ channel blockers, Phenytoin

40
Q

Which drugs cause Hyperuriciemia (gout)?

A

Pyrazindamide,Thiazides, Furosemide, Niacin, Cyclosporine

41
Q

Which drugs cause Osteoporosis?

A

Corticosteroids, depot medroxyprogesterone acetate, GnRH agonists, aromatse inhibitors, anticonvulsants, heparin, PPIs

42
Q

Which drugs cause myopathy?

A

Statins, fibrates, niacin, colchicine, daptomycin, hydroxychloroquine, interferon-A, penicillamine, glucocorticoids

43
Q

Which drugs cause photosensitivity?

A

Sulfonamides, amiodarone, Tetracyclines, 5-FU

44
Q

Which drugs cause Rash (Steven-Johnson Syndrome)?

A

Anti-epileptic drugs (lamogtigone), allopurinol, sulfa drugs, penicillin

45
Q

Which drugs cause teeth discoloration?

A

Tetracyclines

46
Q

Which drugs cause tendon and cartilage damage?

A

Fluoroquinolones

47
Q

Which drugs cause Cinchonism?

A

Quinidine, Quinine

48
Q

Which drugs present with Parkinson-like Syndrome?

A

Antipsychotics, Resperipine, Metoclopromide

Cogwheel Rigidity of the ARM

49
Q

Which drugs cause peripheral neuropathy?

A

Phenytoin, Vincristine

50
Q

Which drugs cause Pseudotumor cerebri?

A

Growth hormones, tetracyclines, Vitamin A

51
Q

Which drugs cause seizures?

A

Isoniazid, (Vitamin B6 deficiency), Bupropion, Imipenem/cilastatin, Tramadol, Enflurane

BIITE my tongue during seizures

52
Q

Which drugs cause Tardive Dyskinesia?

A

Antipsychotics, metoclopromide

53
Q

Which drugs cause visual disturbance?

A

Topiramate (diplopia/blurred vision), Digoxin (yellow-tinged), isoniazid (optic neuropathy/ color vision changes), Vigabatrin (bilateral visual field defects), PDE-5 inhibitors (blue-tinged vision), Ethambutol

These Drugs Irritate Very Precious Eyes

54
Q

Which drugs cause antimuscarinic effects?

A

Atropine, TCAs, H1-blockers, antipsychotics

55
Q

Which drugs cause disulfiram-like reactions?

A

1st generation Sulfonylureas, Procarbazine, certain Cephalosporins, Griseofulvin, Metronidazole

56
Q

Which drugs cause nephrotoxicity/ototoxicity?

A

Loop diuretics, Aminoglycosides, cisplatin, Vancomycin, amphotericin B

Pharmacology Term 4 (3 decks)

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