RSI Drugs

Question 1

Sedative/ Induction Agents

Answer 1

Etomidate (Amidate)
Ketamine
Propofol (Diprivan)
Midazolam (Versed)

Question 2

Paralytics

Answer 2

Succinylcholine
Rocuronium
Vecuronium (rarely used)

Question 3

Etomidate

Answer 3

0.3mg/kg IV
15-45sec
3-10 min
\+: No change in BP
-: adrenal suppression (concern in sepsis)

Question 4

Ketamine

Answer 4

1 mg/kg IV, with max loading dose of 50mg/kg (NMDA receptor)
30-45s
20 min
+: No change in BP, bronchodilator, analgesia, dissociative amnesia
-: may cause ICP rise, allergic reaction

Question 5

Propofol

Answer 5

1-2.5mg/kg IV
20-40s
5-10min
\+: post intubation sedation, bronchodilator, status epilepticus
-: Hypotension

Question 6

Succinylcholine

Answer 6

1.5mg/kg IV
45-60s
5 min
+: rapidly extubated after elective procedure
-: hyperkalemia, malignat hyperthermia, burns, crush injury/neuromuscular disorder, bradycardia

Question 7

Rocuronium

Answer 7

1 mg/kg IV
60s 
30 mins
\+: longer acting 
-: can not be rapidly extubated

Question 8

Midazolam (Versed)

Answer 8

0.3mg/kg
+: Conscious sedation
-: Hypotension

Question 9

Premedication

Answer 9

Atropine in babies <1yo w/ bradycardia
0.02mg/kg
Fentanyl