RSI Drugs Flashcards
Etomidate (Amidate)
Name/Class: ETOMIDATE (Amidate)/Hypnotic
Description: Etomidate is an ultra–short-acting nonbarbiturate hypnotic with no analgesic effects and limited cardiovascular and respiratory effects.
Indications: Induce sedation for rapid sequence intubation.
Contraindications: None.
Precautions: Head Injury if no paralytics used, marked hypotension, severe asthma, or severe cardiovascular disease.
Dosage/Route: 0.1 to 0.3 mg/kg IV over 15 to 30 sec.
Pedi: children > 10 years, same as for adults
Midazolam (versed)
Name/Class: MIDAZOLAM (Versed)/Sedative
Description: Midazolam is a short-acting benzodiazepine with CNS depressant, muscle relaxant, anticonvulsant, and anterograde amnestic effects.
Indications: To induce sedation before cardioversion or intubation, Seizures
Contraindications: Hypersensitivity to benzodiazepines, narrow-angle glaucoma, shock, coma, or acute alcohol intoxication.
Precautions: COPD, renal impairment, CHF, elderly.
Dosage/Route: 1 to 5 mg slow IV/IM; 3 mg intranasal;
Pedi: 0.05 to 0.2 mg/kg IV: 0.1 to 0.15 mg/kg IM;.
PANCURONIUM (Pavulon)
Name/Class: PANCURONIUM (Pavulon)/Nondepolarizing Neuromuscular Blocker
Description: Pancuronium is a nondepolarizing neuromuscular blocker that causes paralysis without bronchospasm or hypotension, it does not cause the fasciculations associated with polarizing agents.
Indications: To facilitate endotracheal intubation.
Contraindications: Tachycardia.
Dosage/Route: 0.04 to 0.1 mg/kg IV.
Pedi: same as adult.
PROPOFOL (Diprivan)
Name/Class: PROPOFOL (Diprivan) Sedative hypnotic, short-acting
Description: Produces rapid and brief state of general anesthesia
Indications: Anesthesia induction, anesthesia maintenance, sedation for mechanically ventilated patients.
Contraindications: Hypovolemia, known sensitivity including soybean oil, peanuts, and eggs.
Precautions/Side Effects: Seizure, apnea, dysrhythmias, asystole, hypotension, hypertension.
Dosage/Route: Induction dose: 1.5-3 mg/kg IV, IO. Maintenance infusion: 25-75 ug/kg/min IV, IO.
Pedi: Induction dose: 2.5-3.5 mg/kg IV, IO. Maintenance infusion 125-300 ug/kg/min IV, IO
ROCURONIUM BROMIDE (Zemuron)
Name/Class: ROCURONIUM BROMIDE (Zemuron) Nondepolarizing neuromuscular blocker
Description: Antagonizes acetylcholine at the motor end plate producing skeletal muscle paralysis.
Indications: Rapid sequence intubation
Precautions/Side Effects: Bronchospasm, wheezing, rhonchi, respiratory depression, apnea, dysrhythmias, tachycardia.
Dosage/Route: 0.6-1.2 mg/kg IV, IO
Pedi: Same
SUCCINYLCHOLINE (Anectine)
Name/Class: SUCCINYLCHOLINE (Anectine)/Depolarizing Neuromuscular Blocker
Description: Succinylcholine is an ultra–short-acting depolarizing neuromuscular blocker.
Indications: Facilitated endotracheal intubation.
Contraindications: Family history of malignant hyperthermia, penetrating eye injury,
narrow-angle glaucoma. Hyperkalemia, Crush Injury, burns over 24 hours, Mystina Gravitas, MS, ALS
Precautions: Severe burns; spinal cord injury;
Dosage/Route: 1 to 1.5 mg/kg IV/IM.
Pedi: 1 to 2 mg/kg IV/IM.
VECURONIUM (Norcuron)
Name/Class: VECURONIUM (Norcuron)/Nondepolarizing Skeletal Muscle Relaxant
Description: Vecuronium is a nondepolarizing skeletal muscle relaxant similar to pancuronium with minimal cardiovascular effects.
Indications: Facilitated endotracheal intubation.
Contraindications: None.
Precautions: Hepatic or renal impairment, impaired fluid and electrolyte or acid/base balance, severe obesity, myasthenia gravis, elderly, debilitated patients, or malignant hyperthermia.
Dosage/Route: 0.1 mg/kg IV.
Pedi: same as adult.
