routes of drugs administration Flashcards
a process by which drugs enter blood stream without being chemically altered
drug absorption
factors influencing rate of absorptions
physiochemical properties of drugs
routes of administration
dosage form
circulation at site of absorption
drug concentration
mechanism of absorption
passive diffusion
filtration
endocytosis
active transport
routes of drug administration
enteral [ placed directly into gastrointestinal truct]
parenteral
enteral routes
sublingual or buccal; placed under tongue
oral
rectum
parenteral routes
intravascular
intramuscular
subcutaneous
intravenous
intravenous
has precise and accurate onset of action
large amount can be given
has high risk of adverse effects
30 to 60 sec
intramuscular
pain at injection sites
for oily or suspension drugs
10 to 20 min
subcutaneous
slow absorption
absorption limited by blood flow
15 to 30 min
inhalation
for gaseous, volatile substances and aerosols
rapid onset of action due to rapid reach circulation
2 to 33 min