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PHA312 > Routes Of Drug Excretion > Flashcards

Routes Of Drug Excretion Flashcards

1
Q

Examples of drugs excreted via biliary/faecal route

A

Vancomycin, Vincristine

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2
Q

Examples of drugs excreted via saliva

A

Caffeine
Phenytoin
Diazeoam
Lithium

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3
Q

Examples of drugs excreted via tears

A

Cytarabine

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4
Q

Examples of drugs excreted via lungs

A

General anaesthetics
Alcohol

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5
Q

Examples of drugs excreted via sweat

A

Alcohol
Antipyrine
Cocaine
Salicylic acid
Lead

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6
Q

Examples of drugs excreted via hair

A

Phenobarbital
Methamphetamine
Methoxyphenamine

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7
Q

Examples of drugs excreted via breast milk

A

Aspirin

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8
Q

Which class of drugs are mostly excreted via breast milk and why?

A

Basic drugs. It’s pH is lower than plasma.

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9
Q

Drugs administered weekly

A

Fluoxetine

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10
Q

Examples of drugs that undergo enterohepatic recycling

A

Tetracycline
Chloramphenicol
Digitoxin
Phenytoin

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11
Q

Normal GFR

A

90 to 130 ml/min/1.73m^2

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12
Q

Stage 2 chronic kidney disease GFR

A

60-89 ml/min/1.73m^2

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13
Q

Kidney failure GFR

A

Less than 15 ml/min/1.73m^2

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14
Q

Creatinine clearance in men and women

A

120 mL/min, 95 ml/min

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15
Q

Basic drugs

A

Quinine
Probenecid
Morphine
Histamine
Serotonin
Dopamine
Pethidine

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16
Q

Acidic drugs

A

Aspirin
Penicillin
Methotrexate
Indomethacin
Frusemide
Thiazide diuretics.

17
Q

Urine alkalinizing drugs

A

Sodium bicarbonate
Acetazolamide
Potassium citrate

18
Q

Urine acidifying drugs

A

Aspirin
Penicillin
Methotrexate
Indomethacin
Frusemide
Thiazide diuretics

19
Q

Stage 3a chronic kidney disease GFR

A

45-59 ml/min/1.73m^2

20
Q

Stage 3b chronic kidney disease GFR

A

30-44 ml/min/1.73m^2

21
Q

Stage 4 CKD GFR

A

15-29 ml/min/1.73m^2

PHA312 (5 decks)

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