Routes Of Administration Flashcards
Local
Site Of Administration Is The Site Of Action
Systemic
Drug Must Be Absorbed & Distributed Throughout The Body Via Blood
Systemic Routes Of Administration
Oral Intravenous (IV) Subcutaneous (SQ, SC) Intramuscular (IM) Intraperitoneal (IP) Inhalation
Oral Administration Advantages
Safe
Convenient In Some Animals
Economical - Cheap
No Problem Of Infection
Oral Administration Disadvantages
Inactivation (Sometimes) By Gastric Acidity, Digestive Enzymes, Or Rumen Microflora
Food Or GI Activity May Affect Absorption
Irritant Drugs May Cause Vomiting & Diarrhea
Slow Onset Of Action
Some Bad Tasting Drugs
IV Advantages
Accurate
Fast Onset Of Action
Irritant, Hypertonic, Acidic & Basic Drugs Can Be Given
Large Volumes Can Be Given
IV Disadvantages
Dangerous
IM Advantages
Rapid Absorption
Duration Of Action Exceeds IV
Suspensions Can Be Injected
IM Disadvantages
Irritant, Hypertonic, Acidic & Basic Drugs May Cause Tissue Damage
SQ/SC Advantages
Slow Absorption But Constant
Longer Duration Of Action
SQ/SC Disadvantages
Slow Onset
Irritating Drugs Cannot Be Used