Posology Flashcards

1
Q

Posology

A

Study of Doses

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2
Q

Dose

A

Amount of drug given to an animal to give a certain effect

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3
Q

Dosage

A

Amount of drug per unit body weight

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4
Q

3 Types Of Doses

A

Therapeutic (Effective) Dose
Toxic Dose
Lethal Dose

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5
Q

Minimal Therapeutic Dose

A

Smallest amount having a therapeutic effect

Lower than this is an Ineffective Dose

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6
Q

Maximal Therapeutic Dose

A

Largest amount tolerated without producing toxic effect

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7
Q

Therapeutic Dose

A

Optimal Dose, which lies somewhere between the minimal and maximal therapeutic doses

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8
Q

Toxic Dose

A

Amount that produces undesirable clinical, hematological, biochemical, or pathological alterations

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9
Q

Therapeutic Index/Ratio (TI)

A

Ratio between LD50/ED50

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10
Q

Standard Safety Margin (SSM)

A

Expresses the percentage dose increase between ED99 and LD1

More accurate than TI

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