Posology Flashcards
Posology
Study of Doses
Dose
Amount of drug given to an animal to give a certain effect
Dosage
Amount of drug per unit body weight
3 Types Of Doses
Therapeutic (Effective) Dose
Toxic Dose
Lethal Dose
Minimal Therapeutic Dose
Smallest amount having a therapeutic effect
Lower than this is an Ineffective Dose
Maximal Therapeutic Dose
Largest amount tolerated without producing toxic effect
Therapeutic Dose
Optimal Dose, which lies somewhere between the minimal and maximal therapeutic doses
Toxic Dose
Amount that produces undesirable clinical, hematological, biochemical, or pathological alterations
Therapeutic Index/Ratio (TI)
Ratio between LD50/ED50
Standard Safety Margin (SSM)
Expresses the percentage dose increase between ED99 and LD1
More accurate than TI