Route of drug administration

Question 1

Which of the following factors influences the choice of a drug administration route?
A) The drug’s physical and chemical properties
B) The site of desired action
C) The patient’s condition
D) All of the above

Answer 1

D

Question 2

Which of the following is an advantage of oral drug administration?
A) Faster onset of action than intravenous administration
B) Less variability in drug absorption
C) Safer, convenient, and non-invasive
D) Bypasses first-pass metabolism

Answer 2

C

Question 3

Which drug administration route bypasses the first-pass metabolism?
A) Oral
B) Sublingual
C) Rectal
D) Intramuscular

Answer 3

B

Question 4

Why is the parenteral route preferred for unconscious patients?
A) It is less expensive
B) It avoids gastrointestinal absorption issues
C) It allows for slower drug absorption
D) It prevents first-pass metabolism

Answer 4

B

Question 5

A 7-year-old child presents with acute pneumonia and requires antibiotic therapy. Which route of drug administration is most appropriate?
A) Enteral
B) Rectal
C) Intravenous
D) Inhalational

Answer 5

C

Question 6

Which of the following is NOT a limitation of oral drug administration?
A) Drug degradation by digestive enzymes
B) Difficult to use in vomiting patients
C) Variation in absorption rates
D) Rapid onset of action

Answer 6

D

Question 7

What is the primary advantage of the transdermal route?
A) Immediate systemic effects
B) Avoids first-pass metabolism
C) Suitable for large drug molecules
D) No risk of skin irritation

Answer 7

B

Question 8

Which of the following is an example of a drug commonly administered through the sublingual route?
A) Diazepam
B) Glyceryl trinitrate
C) Insulin
D) Morphine

Answer 8

B

Question 9

Which of the following is NOT a characteristic of the rectal route?
A) Useful for irritant drugs
B) Bypasses first-pass metabolism partially
C) Suitable for unconscious patients
D) Rapid and predictable absorption

Answer 9

D

Question 10

Which statement about inhalational drug administration is correct?
A) It is only used for systemic effects
B) It is slower than oral administration
C) It provides rapid drug absorption
D) It is ineffective for volatile drugs

Answer 10

C

Question 11

Which of the following is an example of a drug administered by the transdermal route?
A) Diazepam
B) Nicotine patch
C) Paracetamol
D) Lidocaine injection

Answer 11

B

Question 12

Which parenteral route provides the most immediate drug effects?
A) Intramuscular
B) Subcutaneous
C) Intradermal
D) Intravenous

Answer 12

D

Question 13

What is the primary limitation of intravenous drug administration?
A) High variability in absorption
B) Risk of overdose and toxicity
C) Slow onset of action
D) Inability to use aqueous solutions

Answer 13

B

Question 14

Which route of drug administration is commonly used for depot preparations?
A) Intravenous
B) Sublingual
C) Intramuscular
D) Transdermal

Answer 14

C

Question 15

Why are aqueous solutions preferred for intravenous injections?
A) They have better lipid solubility
B) They have controlled absorption rates
C) They prevent embolism formation
D) They provide immediate drug action

Answer 15

D

Question 16

What is the primary function of the dermojet in subcutaneous administration?
A) Uses a needle for injection
B) Deposits drug via high-velocity jet
C) Provides a depot effect
D) Requires deep muscle penetration

Answer 16

B

Question 17

Which of the following is a characteristic of intradermal injection?
A) Used for emergency drug administration
B) Forms a bleb at the injection site
C) Provides rapid systemic absorption
D) Used primarily for antibiotic therapy

Answer 17

B

Question 18

Which of the following is NOT an example of a parenteral route?
A) Intramuscular
B) Subcutaneous
C) Sublingual
D) Intravenous

Answer 18

C

Question 19

What is the main disadvantage of the rectal route?
A) Irregular and unpredictable absorption
B) High drug degradation
C) Bypasses first-pass metabolism completely
D) Cannot be used in pediatric patients

Answer 19

A

Question 20

Which of the following routes involves drug administration directly into the bloodstream?
A) Intramuscular
B) Intravenous
C) Subcutaneous
D) Transdermal

Answer 20

B

Question 20

What is the advantage of using nebulizers for drug administration?
A) Direct delivery to the lung
B) Rapid systemic action
C) No risk of overdose
D) Avoids immune system activation

Answer 20

A

Question 21

Which drug administration route is best suited for treating localized skin infections?
A) Sublingual
B) Intravenous
C) Topical
D) Oral

Answer 21

C

Question 22

What is the key difference between transdermal and topical drug administration?
A) Transdermal drugs have local effects, while topical drugs have systemic effects
B) Transdermal drugs bypass first-pass metabolism, while topical drugs do not
C) Topical drugs enter systemic circulation faster than transdermal drugs
D) Transdermal drugs provide immediate effects, while topical drugs are slow-acting

Answer 22

B

Question 22

What is the main function of a nebulizer in drug administration?
A) Converts liquid medication into a mist for inhalation
B) Injects medication into the bloodstream
C) Delays drug absorption in the stomach
D) Prevents drug degradation

Answer 22

A

Question 23

What is the primary advantage of using a depot injection in intramuscular administration? A) Immediate drug action B) Continuous release over time C) Complete first-pass metabolism D) Avoids systemic circulation

Answer 23

B

Question 24

Which of the following routes is NOT classified as enteral? A) Oral B) Sublingual C) Rectal D) Intravenous

Answer 24

D

Question 24

Which parenteral route is used for BCG vaccination? A) Intravenous B) Intramuscular C) Intradermal D) Subcutaneous

Answer 24

C

Question 25

Which of the following drugs is most commonly administered via inhalation for systemic effects? A) Insulin B) General anesthetics C) Aspirin D) Diazepam

Answer 25

B

Question 26

Which of the following is a disadvantage of subcutaneous drug administration? A) Only aqueous solutions can be used B) Drug absorption is very slow C) It cannot be self-administered D) It requires hospital admission

Answer 26

B

Question 27

What is the primary reason that intravenous administration has 100% bioavailability? A) It bypasses the first-pass effect and digestive system B) It allows for depot formation C) It slows down drug metabolism D) It requires high doses of medication

Answer 27

A

Question 28

A 60-year-old patient with chronic heart disease is prescribed glyceryl trinitrate for acute angina. Which route should be used for the fastest relief? A) Oral B) Intramuscular C) Sublingual D) Transdermal

Answer 28

C

Question 29

A 4-year-old child presents with seizures and needs immediate drug administration. Which route is the most suitable for rapid absorption? A) Oral B) Rectal C) Intramuscular D) Subcutaneous

Answer 29

B

Question 30

A patient requires a continuous and predictable drug release over 24 hours for nicotine withdrawal therapy. Which route is most appropriate? A) Oral B) Intravenous C) Transdermal D) Inhalation

Answer 30

C

Question 31

A patient is diagnosed with bacterial meningitis and requires immediate antibiotic therapy. Which route of administration is preferred? A) Intramuscular B) Intravenous C) Oral D) Sublingual

Answer 31

B

Question 32

A patient in anaphylactic shock is given epinephrine. What is the preferred route of administration for the fastest action? A) Subcutaneous B) Intramuscular C) Oral D) Rectal

Answer 32

B

Question 33

A patient with severe vomiting needs anti-nausea medication. Which route of administration is best to avoid drug loss? A) Oral B) Intravenous C) Rectal D) Transdermal

Answer 33

C

Question 33

A comatose patient requires long-term nutritional support. Which route of drug administration is most suitable? A) Sublingual B) Rectal C) Oral D) Parenteral

Answer 33

D

Question 34

A patient undergoing chemotherapy experiences severe nausea. Which drug administration route is preferred to deliver medication continuously? A) Oral B) Intravenous infusion C) Transdermal patch D) Sublingual

Answer 34

B

Question 35

A patient with asthma is prescribed a bronchodilator for rapid relief of symptoms. Which administration route is most effective? A) Intravenous B) Oral C) Inhalation D) Transdermal

Answer 35

C

Question 35

A burn patient requires analgesia for severe pain. Which of the following routes would provide the fastest relief? A) Intravenous B) Oral C) Subcutaneous D) Transdermal

Answer 35

A