ROQs Flashcards
What is bright on T1?
Fat
What is bright on T2
CSF
How does gray matter appear on T1?
darker than white matter
How does gray matter appear on T2?
Brighter than white matter
Ir-192 half-Life?
74 days
Which unsealed source requires bystander shielding?
I-131, as it emits gamma rays.
Sources that release heavier particles (alpha, beta) don’t require shielding as these particles cannot penetrate enough.
Pd-103 half-life?
17 days
What does isobaric mean?
Same atomic mass (protons + neutrons): isobArs. They have different number of protons.
What’re the products of B-plus decay?
Positron + neutrino
What’re the products of B-minus decay?
electron and antineutrino
What happens to Beta-plus (positron) particle after release?
It combines with electrons, annihilates, and releases two gamma rays (0.511 MeV each)
Used in PET imaging
Why is there low dose distribution near the end of a brachytherapy source?
Anisotropy function:
The anisotropy means the dose is directionally dependent. Think of a radioactive seed as a paper towel roll tube. Holding the tube vertical and looking at the center of the tube, you see the whole tube. Now, rotate the tube to look through the hole like a telescope (come on, we’ve all done that). As the tube is rotated, you see less and less of it until all you see is the hole. For the brachytherapy source, as the measurement point moves from being directly perpendicular to the source, and “seeing” the entire source, to then moving to only “seeing” the tip end-on, the dose rate is going to be different (assuming the same distance from the source, etc.). The dose rate is different because of the self-shielding of the source (“seeing” less of the source), as well as variations in the cladding of the source, which tends to be thicker at the ends, depending on the manufacturer, which attenuates the gammas differently.
What is the purpose of a beam spoiler?
It can increase surface dose through the generation of electrons by the spoiler.
A photon beam spoiler is a panel of low-Z material (often lucite) placed in the beam path close to the skin surface. Because photon interactions with the spoiler produce electron contamination, it is an alternative means to increase the surface dose. Spoilers do not meaningfully diminish beam penetration, unlike bolus, which diminishes beam penetration to a small degree.
Clinical pearl: Varying the thickness of the spoiler and its distance from the patient can be used to achieve or modulate the increase in superficial dose delivered by the treatment.
How should the parallel opposed beams be weighted?
The beam closer to the target should be weighted more heavily. This minimizes hotspots w/o minimizing coverage.
How does Strontium-89 decay?
Sr-89 decays via beta- decay, forming Yt-89
What is Strontium-89 used for?
it is a radiopharmaceutical used to treat osseous mets. It is preferentially absorbed in the bones and releases B- particles within the metabolically active bone met.
What is coherent scattering?
An incoming photon interacts with an electron and changes direction w/o losing energy. It’s in the name, scatter: nothing is created. Photons are merely scattered.
What is internal conversion?
A higher-energy nucleus transfers energy to an orbiting electron, ejecting it.
Its in the name: conversion of energy into kinetic energy for an electron.
What is the photoelectric effect (note NOT internal photoelectric)?
An incoming photon ejects an inner shell electron. An outer shell electron fills this vacancy, releasing energy in the form of characteristic XR.
What is internal photoelectric effect (stress on internal)
Characteristic XR generated by photoelectric effect is absorbed by outer shell electrons, ejecting them (auger electron).
What are the generic quality management tools in order of importance?
- Forcing functions and constraints
- Automation and computerization
- Protocols, standards, and information
- Independent double-check systems and redundancies
- Rules and policies
- Education
What is a forcing function?
A forcing function is an aspect of a design that prevents the user from taking an action without consciously considering information relevant to that action. It “forces” conscious attention upon something.
Why is Radium-226 no longer used in brachytherapy?
- Large in size, difficult to achieve conformal distributions
- LONG half-lives (1600 years) making it difficult to dispose
- Average emitted energy is high (0.83 MV (max 2.45 MeV)) making it difficult to shield.
However, it can be used with the Patterson-Parker system. The system was designed to be used with Ra.
What is the half-life of Ra-226?
1600 years
What isodose line defines field size?
50%
What entity is proportional to the maximum XR photon energy in an XR tube?
Voltage
In an XR tube, what happens to the average XR energy if the voltage is increased?
Increases
In an XR tube, what is the relationship between the max energy of an XR and the average energy of the XRs?
Ave = 1/3 * Max
What does the picket fence test?
Individual and relative MLC positions
Why is secondary shielding used with LINACs performing IMRT vs. 3D?
To protect against secondary sources of radiation.
- Scatter: Radiation scattered out of the patient. This depends on the dose delivered at the isocenter. This is usually significantly lower in energy than the primary beam.
- Leakage: Radiation that escapes from the treatment head. With IMRT, there is an increase in the MU, therefore there is more leakage. Leaked radiation has the same energy as the primary beam, which needs additional shielding.
What is the difference between SSD and SAD setups?
What is the preferred dosimetric technique for measuring beam profiles for very small field sizes in SRS?
Film! Lol.
What is the rule of thumb for how much radioactive material decays per day during its first half-life?
1% per day
For I-125 implants, when can a patient be released to the general public?
When the dose rate at 1 m is 0.01 mSv/hr or total activity is < 9 mCi.
Ensure dose < 5 mSv to any individual (spouse, etc).
For Pd-103 implants, when can a patient be released to the general public?
When the dose rate at 1 m is 0.03 mSv/hr
For Ir-192 implants, when can a patient be released to the general public?
When the dose rate at 1 m is 0.008 mSv/hr
For I-131 implants, when can a patient be released to the general public?
When the dose rate at 1 m is 0.07 mSv/hr
What do TLDs and OSLDs measure?
Cumulative radiation exposure
What stimulates TLDs vs. OSLDs
TLDs: Stimulated by heat
OSLDs: Stimulated by light
Which can be re-read, TLDs or OSLDs?
OSLDs
TLDs can only me re-read once
Which can be reused after reannealing, TLDs or OSLDs?
Both
How do we measure beam flatness?
Note Max Intensity (Max) and Min (Min) intensity over the inner 80% of the field at 10 cm depth.
Then, F = (Max-Min)/(Max+Min)*100
What does beam flatness depend on?
Field size, beam energy, and depth.
How is electron beam energy defined when using a LINAC in electron mode?
The energy of the electrons at the entrance surface (NOT when it exits the machine)
Are electrons produced by a LINAC mono or polyenergetic?
Monoenergetic (all have roughly the same energy)
How is an electron beam spread out in a LINAC?
Using a scattering foil (as opposed to a target)
What is the maximum amount of energy shared by a photon with an electron in a Compton interaction?
75%
Occurs when a photon is backscattered and retains about 25% of the energy.
What is Compton scatter?
It is the principal interaction of photons with matter. Photon interacts with free or valence (loosely bound) electrons and scatters in a different direction, imparting some energy to the electron.
It is directly proportional to the number of outer shell electrons and the density of the material. Only weakly proportional to photon energy.
Does the linear attenuation coefficient depend on the density of a material?
Yes
What is the mass attenuation coefficient?
It is the linear attenuation coefficient normalized to density.
mass atten coeff = (lin atten coeff)/density
How do the linear attenuation coeff of water, ice, and steam compare?
Steam < Ice < Water
Water is denser than ice!
What is tissue-air ratio (TAR)?
It is the dose along the central axis of a beam as compared to some reference (air, etc)
What does tissue-air ratio (TAR) depend on?
TAR:
- Increases with beam energy and field size (2/2 increased contribution from scatter photons)
- Decreases with increasing depth 2/2 attenuation
What does the percentage depth dose (PDD) depend on?
Increases with
- Beam energy 2/2 increased penetrance
- Increasing field size 2/2 increased scatter photons
- Increasing SDD
Decreased with
- Increasing depth 2/2 inverse square law and attenuation
Is PDD more convenient for SSD or SAD setups?
SSD
What is the advantage of pencil beam scanning vs. passive scattering when using protons?
PCB achieves more conformal proximal conformality. Distant conformality is the same between the two!
What is the disadvantage of pencil beam scanning for protons?
Can miss the tumor due to motion, therefore, it is necessary to gate (respiratory, etc)
What are the components of a passive scattering arrangement for protons?
- Scattering foil: Spreads out proton beam laterally
- Patient-Specific Apertures: Conform beam to the tumor shape
- Compensator: Shapes the range of the proton beam to conform to the distal end of the target. It spreads the Bragg peak, which results in a more proximal dose than with PCB.
What are the contributors to the primary dose along the central axis of a LINAC beam?
Primary beam energy, followed by beam scatter (secondary, usually <10%).
Note that the scatter component increased with depth (primary beam is attenuated and scattered), field size.
At what activity level is a sealed source considered leaky?
> 185 Bq
0.005 uCi
How does surface dose depend on beam energy and field size?
Increased by:
- increased field size
- deceased beam energy (up to 10 MV)
- Increased beam angle (beam enters obliquely)
- decreased tray-to-skin difference (dose from e-contamination)
What are the different wedges used?
- Physical (steel, lead): placed in the beam path, and produce the largest scatter
- Universal: located inside the LINAC head. Less scatter than a physical wedge.
- Dynamic (MLCs): Least amount of scatter. Uses variable dose rates
What is the half-life of Cs-137?
30 years
What is “quenching” in radiation detectors?
Prevents a single ionization event from registering as multiple events. So every event is “quenched?”
What is chemical “quenching” in radiation detectors?
Halogen gas additive in a radiation detector absorbs UV light emitted by single radiation events.
What is electronic “quenching” in radiation detectors?
Transient reduction in anode voltage after an event is detected. Leads to a dead time, during which another event cannot be recorded.
What is a half value layer?
It is the thickness of a material required to reduce radiation intensity to half its original value.
How to the first and second half value layers compare with one another (HVL1 vs. HVL2)?
For monoenergetic beams, HVL1 = HVL2.
For polyenergetic beams, the beam becomes hardened as it passes through the first HVL. Therefore, the second HVL is larger than the first (higher energy photons left): HVL2 > HVL1.
What peak kilovoltage (kVp) across an XR tube produces diagnostic XRs?
20-120 kVp
What peak kilovoltage(s) across an XR tube generate therapeutic XRs?
Superficial: 50-150 kV
Orthovoltage: 150-500 kV
Megavoltage: ≥ 1 MV
Note diagnostic XRs (20-120 kVP) and superficial XRs have a significant amount of overlap.
How do head scatter (Sc) and phantom scatter (Sp) vary with field size?
Increase with field size as more photons/electrons are available to be scattered into the central axis of the beam with increasing field sizes.
What part of the LINAC is responsible for the head scatter (Sc)?
The jaws are responsible for it. Tertiary field shaping (MLCs) also scatter, but this is negligible compared to the jaws.
What contributes to phantom scatter (Sp)?
Tertiary scatter (MLCs)
Field Size
What is the advantage of on-board MV-CBCT imaging as opposed to kV-CBCT?
Less susceptibility to artifacts caused by high Z objects (metallic implant/fillings).
What is the advantage of kV-CBCT over MV?
Better image quality at much lower doses.
What are isotones?
Same number of neutrons.
What are isotopes?
Same mass and atomic number but differ in their energetic states (one usually has a higher energy).