Rocuronium bromide

Question 1

Clinical condition or situation to which this PGD applies

Answer 1

Neuromuscular relaxation following return of spontaneous circulation (ROSC) following cardiac arrest in an intubated patient

Question 2

Inclusion criteria

Answer 2

Cardiac arrest patient who has already undergone successful ends-tracheal intubation during resuscitation (confirmed by ETCO2 who then has a ROSC and is not tolerating the tube

Should be used in conduction with sedation - normally morphine and midazolam

Adult patients only

Question 3

Exclusion criteria

Answer 3

Paediatric patients

Patients who do have a positively confirmed ET Tube

Hypersensitivity to rocuronium bromide

Question 4

Cautions

Answer 4

Care should be taken to ensure the patient has adequate sedation

Should not be mixed with alkaline solutions

Question 5

Dose and frequency

Answer 5

0.6mg/kg, repeat doses guided by response to prior dose

Question 6

Form and strength

Answer 6

10mg/ml pre-filled at the beginning of the shift.

Question 7

Adverse effects

Answer 7

Injection site pain/reaction, changes in vital signs and prolonged neuromuscular block

Anaphylactic and anaphylactoid reactions are the most frequently reported serious adverse side effect