Robbins Ch. 20 - The Kidney IV Flashcards by Matt Stanton | Brainscape

Q

VHL

A

renal cell carcinoma

chromosome 3

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Q

risk facrors for renal cell carcinoma

A

smoking, HTN, obesity, asbestos, heavy metals

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Q

hereditary papillary carcinoma

A

MET mutation

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Q

trisomy 7 and 17

A

papillary carcinoma

-MET mutations

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Q

chromophobe carcinoma

A

subset of RCC

-halo around nucleus

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Q

Xp11 translocation carcinoma

A

TFE3 mutation

clear cytoplasm in papillary formation
young patients

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Q

likely to invade renal vein?

A

hematogeous spread

-renal cell carcinoma

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Q

triad for renal cell carcinoma

A

hematuria, CVA tenderness, palpable mass

also - fever, malaise, weakness, weight loss

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Q

urothelial carcinoma of renal pelvis

A

hematuria

50% concomitant bladder tumor

bad prognosis (esp. high grade)

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Q

triphasic wilms

A

stromal
epithelial
blastemal

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