Risk Management Flashcards
May cause increased heart rate, convulsions, death,
or may burn eyes and skin
- combustible ad should be used with exercised
caution, under a hood,
PHENOL
Should be stored away from acids, and should not be
mixed with formaldehyde as this generates heat and
toxic vapors that can be irritating to the respiratory
system
AMMONIUM HYDROXIDE
May be used in replace mercuric oxide when
reconstituting Harris hematoxylin
SODIUM IODATE
Explosive when dry or when combined with metal or
metallic salts
PICRIC ACID
Can cast frost bites or thermal (cold) burns
NITROGEN
Concentrated acid is particularly dangerous because
of its fumes, and should be handled under a fume
hood, using goggles, apron and gloves.
HYDROCHLORIC ACID
Toxic to the reproductive, urinary and blood systems
when inhaled or ingested
ETHYLENE GLYCOL
Can irritate the skin and the eyes, and can corrode
metal. Should be handlesd under a chemical fume
hood
FORMIC ACID
Carries minimal health risk when used in histology
under normal conditions
SODIUM THIOSULFATE
Excessive exposure may cause drowsiness, headache,
nausea and cyanosis.
ANILINE
- Should not be disposed by pouring down the drain
since they may form explosive picrates with metal
pipes
PICRIC ACID
Strong irritant to skin, eyes and respiratory system
- Corrosive to most metals
SULFURIC ACID
Moderate skin and eye irritant, and is toxic by
ingestion and inhalation. It may cause blindness or
death if taken in excessive amounts
METHANOL
Identifying, _assessing, and controlling threats to
every individual in hospital Facility
Risk Management
Enumerate the common Histotech equipments
● Microscopes
● Microtome
● Cryostat
● Autotechnicon
● Automated coverslipper
● Automated H and E stainer
Mild to moderate irritation of the skin, eyes,
dangerously flammable and volatile.
ETHANOL
Strong oxidant, eye irritant and corrosive to most metals; Do not mix with formaldehyde or
diaminobenzidine
SODIUM HYPOCHLORITE (liquid chlorine bleach)
Because it is a strong oxidant, it should not be mixed with acetic acid, ammonium hydroxide, ethanol, ethylene glycol, formaldehyde, hydrochloric acid, hydrogen peroxide, or sulfuric acid
POTASSIUM PERMANGANATE
can cause frostbite; Excessive exposure to vapors may cause irritation of the respiratory tract, cough and irregular breathing
ISOPENTANE
Relatively safe when used as a fresh solution, but can
be explosive when solution becomes old
SILVER SALTS
Common size that a microtome could cut
1-10 mm thick
Carcinogenic and can affect the liver, reproductive
organs, central nervous system, blood and gastrointestinal tract. Excessive exposure to the vapor can cause disorientation, loss of consciousness and death.
CHLOROFORM
can be recycled by distillation or by drain disposal, can be detoxified by a commercial
product, or can be disposed of by a licensed waste
hauler
FORMALDEHYDE
Corrosive to eyes and mucous membranes; Vials must be stored, broken and opened under a hood, not in the open air
OSMIUM TETROXIDE
Toxic to kidneys, corrosive to the skin and mucous
membranes and cause cancers. All forms of skin
contact should be avoided.
CHROMIC ACID
microtome for biological samples
Vibrating microtome
Repeated exposure can cause impaired memory,
poor coordination, mood swings and permanent
nerve damage
TOLUENE
Can cause mild to moderate irritation of the skin and
eyes, and is toxic by ingestion
ISOPROPANOL
Corrosive to skin, mucous membranes and most
metals. It is toxic by inhalation
NITRIC ACID
Relatively safe when used in dilutions prescribed for
histologic use; When concentrated, it is corrosive and causes severe burns of the eyes, skin and mucous membranes; Repeated skin contact can cause dermatitis and slow-healing ulcers
OXALIC ACID
Corrosive to eyes and skin
HYDROXIDE (SODIUM AND POTASSIUM)
Corrosive to most metals, including stainless steel
- Should not be used in tissue processors
ZINC CHLORIDE
Less toxic substitute for ethylene – based ethers
PROPYLENE GLYCOL
micrtome for exteremely thin sections
Ultramicrotome
Should be restricted or avoided if possible, except as
diluent in mounting media or for removing coverslips
TOLUENE
microtome for frozen samples
Cryostat
Toxic when absorbed by the skin, can cause severe
irritation of the eyes, and is a potential carcinogen.
ANILINE
Can cause severe irritation of the eyes and skin, and
are corrosive to metal b
MERCURIC CHLORIDE/MERCURIC OXIDE
reagent must be handled under a fume hood, with
vinyl gloves
ETHYLENE GLYCOL
Extremely flammable and highly volatile
- Should be stored only in a refrigerator or freezer that
is especially suited for explosive atmosphere
ISOPENTANE
Can cause severe irritations of the eyes and skin, and
toxic by ingestion.
GLUTARALDEHYDE
Harmless # used in concentrations less than 5%
HYDROGEN PEROXIDE
Very toxic and may be fatal when swallowed or
absorbed through the skin or when mixed with
SODIUM AZIDE
Reagents used to “de-zekerize” ; may be replaced with zinc formalin or glycosal solutions
MERCURIC CHLORIDE/MERCURIC OXIDE
