Rickettsia and Chlamydiae and Mycoplasma

Question 1

General Rickettsiae

FLIP

Answer 1

Small, intracellular egg/yolk (leakage of important stuff), Grow in cytoplasm and nucleus, and LIVE in arthropods (multiply without causing disease in them).

Question 2

General Rickettsiae

-Special stain

Answer 2

Giemsa’s

Question 3

General Rickettsiae

-Cell components

Answer 3

RNA and DNA - normal
Cell wall - Mucopeptides
*require cofactors

Question 4

General Rickettsiae

-Target cells in host

Answer 4

attacks endothelial cells

Question 5

General Rickettsiae

-General symptoms

Answer 5

SKIN-Petechiae and hemorrhagic rash.

Heart and Brain - Terminal shock = death

Question 6

General Rickettsiae

-test for specific antibodies

Answer 6

Weil-Felix test

Question 7

General Rickettsiae

-Diseases (7)

Answer 7

1-Epidemic typhus (prozwaki) NO Face or palms or feet (kill 40+ yr olds

2-Recurrent Epidemic typhus (BRILL’S disease!)

3-Endemic Typhus (typhi) same as epidemic

4-Rocky Mnt spot fever (rickettsi) Rash is on face and extremities 1st!

5-Rickettsialpox (akari) Mild form R Mnt spot W/black eschar. (oral lesions!!!)

6-Q Fever (Cox Burn) Influenza AIRBORNE Transmission

7-Trench fever (Rochal Quinta) Cold extremities/fever/rash RELAPSES

Question 8

General Chlamydiae

FLIP

Answer 8

Obligate Intracellular
MULTIPLY WITH BINARY FISSION!!!!!

NO PEPTIDOGLYCAN!!!!!

Question 9

General chlamydiae

-2 types

Answer 9

Psittaci- Ornithosis (respiratory)

Trachomatis- BLINDNESS (Gonorrhea)

Question 10

Chlamydia Trachomatis

-Diseases

Answer 10

Trachoma- Granuloma of eye SURFACE (blindness)

Adult Inclusion conjunctivitis- Vascularization with discharge

Neonatal conjunctivitis- Only discharge

Infant pneumonia- Dry cough characteristic

SEX: Urogenital infection- Discharge in men, none in women

SEX: Lymphogranuloma venereum- Painless ulcer that heals and then inflammation and lymphadenopathy and systemic symptoms.

Question 11

Chlamydia General

-Cells infected

Answer 11

Infects epithelial cells

• transitional (bladder etc)
• Columnar (genitals)
• Cuboidal (genitals)

Question 12

General Mycoplasma

-Antibiotic used

Answer 12

tetracycline NOT PENICILLIN

Question 13

General Mycoplasma

-Cell wall/membrane

Answer 13

NO cell wall

Membrane is a triple layer “unit membrane”

Question 14

L forms

Answer 14

Do not cause disease, but allow for relapse.

Question 15

General Mycoplasma

• Normal flora of
• Also found in

Answer 15

Normal flora of mouth

also found in respiratory, genital and urinary.

Question 16

General Mycoplasma

-appearance

Answer 16

FRIED EGG

Question 17

General Mycoplasma

-3 pathologic forms

Answer 17

Mycoplasma Hominis

Mycoplasma pneumonia

*Ureaplasma urealyticum

Question 18

Mycoplasma Hominis

Answer 18

Pyelonephritis

Pelvic Inflammatory disease

Post Hominid (BABY) Fevers

Question 19

Mycoplasma Pneumonia

Answer 19

Pneumonia
Tracheobronchitis
Pharyngitis 
****Eaton's agent
SUPER ANTIGEN
Loss of ciliated cells!

Question 20

Ureaplasma urealyticum

Answer 20

SEX:

Nongonococcla urethritis

Question 21

Strict aerobe and NOT “infants colonized at birth”

Answer 21

M. Pneumonia

Question 22

LGV Lymphogranuloma venerum

Answer 22

***Inguinal/possible buboes

Question 23

Typhus transmission

Answer 23

Louse

Question 24

Reiter’s Syndrome

Answer 24

Chlamydia Trachomatis

Question 25

Lyme’s disease

Answer 25

Erythema migrans