ribhosome Flashcards

1
Q

who discovered ribosome?

A

George Palade

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2
Q

structure of ribosomes

A

Ribosomal RNA (rRNA) and proteins. they are made up of two subunits, one is large is shaped like a dome, and the smaller one forms a cap-like structure over the larger one

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3
Q

What is a dimer and how is it formed?

A

two ribosomal subunit remain united due to the high concentration of Mg^2+ ions in the matrix. reducing the concentration below a certain level leads to the subunits separating, on increasing it the subunit become associated with each other and is known as a dimer.

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4
Q

what is Ergasome?

A

many ribosomes form a chain on a common messenger RNA and form the polyribosomes or polysomes or Ergasome.

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5
Q

what are two types of the ribosome? explain each composition and RNA: protein ratio

A

70s(prokayotic) and 80s(eukaryotic).

1)70s -30s -21 protein and 16 s rRna

The 50s - 34 protein and 23s and 5s rRNA

rna : protein ratio = 60:40

2)80s - 40s -33 protein and a single 18s rRNA

The 60s - 40 protein and three types of

r RNA 28s,5.8,5s

rna:protein = 40:60

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6
Q

functions of ribosomes

A
  1. Ribosomes associated with endoplasmic reticulum synthesize secretory proteins
  2. Free ribosomes synthesize non-secretory proteins. Which is used inside the cell
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7
Q

newly synthesized proteins are processed with the help of wich protein

A

chaperon proteins

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