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Rhumatologie - MKSAP Flashcards

1
Q

Serologic Studies/Associations

Test ANA recherche quoi ?

A
  • SLE = systemic lupus erythematosus
  • SSc = systemic sclerosis = sclérodermie
  • Sjögren syndrome
  • MCTD = mixed connective tissue disease
    titer does not correlate with disease activity
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2
Q

Serologic Studies/Associations

Test anti-SM recherche quoi ?

A

SLE = systemic lupus erythematosus
→ most specific for SLE but does not correlate with disease activity

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3
Q

Serologic Studies/Associations

Test Anti–U1-RNP recherche quoi ?

A

MCTD = mixed connective tissue disease
SLE = systemic lupus erythematosus
→high titer seen in MCTD (>1:10,000 but does not correlate with disease activity)

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4
Q

Serologic Studies/Associations

Test Anticentromere pattern of ANA recherche quoi ?

A

LcSSC = limited cutaneous systemic sclerosis = sclérodermie and CREST syndrome
→ more likely to develop hypertension pulmonaire

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5
Q

Serologic Studies/Associations

Test Anti-dsDNA antibody recherche quoi ?

A

SLE = systemic lupus erythematosus
correlates with disease activity, +++ especially kidney disease !!!

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6
Q

Serologic Studies/Associations

Test Anti-La/SSB antibody; anti-Ro/SSA antibody recherche quoi ?

(6)

A
  • SLE = systemic lupus erythematosus
  • Sjögren syndrome
  • RA = Arthrite rhumatoïde
  • SSc = sclérodermie
  • sicca symptoms
  • neonatal SLE
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7
Q

Serologic Studies/Associations

Test Anti–Scl-70 antibody recherche quoi ?

A

DcSSc = diffuse cutaneous systemic sclerosis; more likely to develop** pulmonary fibrosis**

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8
Q

Serologic Studies/Associations

Test Antihistone antibody recherche quoi ?

A

Drug-induced lupus erythematosus
→ may be seen in primary SLE

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9
Q

Serologic Studies/Associations

Test c-ANCA (anti-PR3 antibody) recherche quoi ?

A

Granulomatosis with polyangiitis

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10
Q

Serologic Studies/Associations

Test p-ANCA (anti-MPO antibody) recherche quoi ?

A

Eosinophilic granulomatosis with polyangiitis and MPA=microscopic polyangiitis

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11
Q

Serologic Studies/Associations

Test Anti–Jo-1 antibody recherche quoi ?

A

Polymyositis and antisynthetase syndrome

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12
Q

Serologic Studies/Associations

Test Anti-CCP antibody recherche quoi ?

A

RA = Arthrite rhumatoïde; may be positive in RF-negative RA

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13
Q

Serologic Studies/Associations

Test Rheumatoid factor recherche quoi ?

A
  1. RA Arthrite rhumatoide
  2. Sjögren syndrome
  3. cryoglobulinemia
  4. common in multiple other diseases (hepatitis C, endocarditis, SLE
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Postgradué (2 decks)

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