RHOGAM Flashcards
what is RHO-gam?
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anti-D immune globulin.
What is RHOGAM
It is an immunoglobulin that helps prevent maternal isoimmunization (self-immunization) or alloimmunization (immunity against another individual of the same species).
Who should receive Rhogham and why?
Rh-negative pregnant woment’
It will helpt o prevent fetal hemolysis and fetal anemia in her future pregnancies.
Coombs test
Test to detect RH antibody in the mother and infant.
Test is done early in pregnancy.
:Detects presence of Rh antibodies in the mother (indirect Coombs test)
and the infant (direct Coombs test).
What is the dose of Rhogam and when it is given?
RhoGAM 300 mcg IM first dose is at 28 weeks.
When is second dose of RHOGAM given?
Give second dose within 72 hours (or sooner) after delivery.
How does RHogam work?
RhoGAM decreases the risk of isoimmunization of the maternal immune system by destroying fetal Rh-positive RBCs that have crossed the placenta.