Rheumatology genetics/immunology Flashcards

1
Q

HLA B27

A

Seronegative sponyloarthropathies:

  • psoriatic arthritis
  • enteropathic arthritis
  • ankylosing spondylitis
  • reactive arthritis
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2
Q

HLA DR2/DR3

A

SLE

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3
Q

Rheumatoid arthritis

A

RF (rheumatoid factor)

anti-CCP (anti-citrullinated peptide)

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4
Q

SLE

A

ANA (anti-nuclear antibodies)
dsDNA (anti-double stranded DNA antibodies)
anti-Smith antibodies

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5
Q

Anti-phospholipid syndrome (Hughes disease)

A

anti-cardiolipin antibodies

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6
Q

Systemic scleroderma

A

anti-topoisomerase antibodies (anti-Scl-70)

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7
Q

CREST syndrome

A

anti-centromere antibodies (ACA)

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8
Q

Polymyositis with pulmonary fibrosis

A

anti-Jo antibodies

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9
Q

Sjogren’s syndrome

A

anti-Ro (anti-SSA)

anti-La (anti-SSB)

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