Rheumatology drugs Flashcards
1
Q
Give examples of DMARDS and what is the first line one used ?
A
1st line one - methotrexate
Other DMARDs include sulphasalazine, hydroxychloroquine and leflunomide.
2
Q
What are the most commonly used biologic theapy drugs in RA?
A
TNF alpha drugs - etanercept, infliximab, adalimumab, certolizumab pegol, and golimumab
3
Q
Give examples of some of the other biologic therapy drug options
A
toclizumab, rituximab and abatacept
4
Q
What do DMARDS increase the risk of ?
A
They are immunosuppressive so infection and bone marrow suppresssion
5
Q
What does treatment with biologics increase the risk of and specifically what in particular ?
A
Increase the risk of infection - esp TB
6
Q
Is methotrexate safe to use in pregnancy ?
A
No!