Rheumatology Flashcards
1
Q
How should folic acid be prescribed for patients taking methotrexate?
A
5 mg once weekly, dose to be taken on a different day to methotrexate dose
2
Q
Methotrexate: Side effects
A
mucositis myelosuppression pneumonitis pulmonary fibrosis liver fibrosis
3
Q
Methotrexate: Reproduction
A
- Women should avoid pregnancy for at least 6 months after treatment has stopped
- Men using methotrexate need to use effective contraception for at least 6 months after treatment
4
Q
Methotrexate: Monitoring
A
‘FBC and renal and LFTs before starting treatment and repeated weekly until therapy stabilised, thereafter patients should be monitored every 2-3 months’
5
Q
Methotrexate: Treatment for toxicity
A
the treatment of choice is folinic acid