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FRACP > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

Anti-CCP

A

RA

Erosive / severe disease

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2
Q

Rheumatoid factor

A

Antibodies to the Fc portion of the IgG
Increases the likelihood of response to rituximab after failing anti TNF Rx

positivity in other conditions:
HCV
rubella
malaria 
SLE 
Sjogrens
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3
Q

anti-jo1

A

The most common myositis specific antibody

antisynthetase syndome
- heliotrop rash, gotrens papules, mechanics hands, raynauds, ILD, fever, non-errosive arthritis

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4
Q

anti-PL-12

A

antisynthetase antibody

usually ILD only > myositis

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5
Q

anti-SRP

A

Myositis specific antibody
specific to polymyositis
Necrotising and severe***

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6
Q

anti-mi-2

A

dematomyositis
more prominent V/shawl sign
good response to therapy

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7
Q

anti-Sm (smith)

A 
SLE
specific*** not sensitive 
African Americans
neuropsych
GN
poor prognosis
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FRACP (12 decks)

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