Nephrology

Question 1

Low complement GN

Answer 1

SLE
Subacute bacterial endocarditis / shunt nephritis /Visceral abscess 
Cryoglobulinaemia 
Post strep/infectious GN (IgG) 
MPGN

Question 2

Normal complement

Answer 2

IgA
Idiopathic RPNG
Immune complex diseases
Vasculidities

Question 3

Causes of membranous nephropathy

Answer 3

1) SLE- class V lupus
2) Drugs - NSAIDS
3) Hep B and C
4) Malignancy - solid organ
5) GVH disease SCT
6) Kidney transplant
7) Syphilis

Question 4

IgA histopathology

Answer 4

also called mesangioproliferative
mesangial hypercellularity
positive immunofluorescence for IgA and C3

*commonest cause of glomerulonephritis world wide
young males
recurrent episodes of haematuria
leads to chronic renal failure
- a/w alcoholic cirrhosis & coeliacs