Rheumatology

Question 1

function units of joints

Answer 1

cartilages

Question 2

what surrounds the cartilage

Answer 2

synovial membrane

Question 3

what does the cartilage meshwork help to entrap

Answer 3

proteoglycan aggregates

Question 4

what do proteoglycan made of?

Answer 4

glycosaminoglycans

-very hydrophilic

Question 5

what does the hydrophilic properties help cartilage do?

Answer 5

pressure of bound water gives cartilage its elasticity

Question 6

what does synovial fluid provide for cartilage?

Answer 6

nutrients.

cartilage is avascular

Question 7

what produces components of articular cartilage?

Answer 7

chondrocytes

Question 8

RA

Answer 8

disease of synovium

Question 9

osteoarthritis

Answer 9

disease of cartilage

Question 10

how thick is the synovial membrane?

Answer 10

only 1-3 cells thick with underlying delicate network of connective tissue (adipose, capillaries, fibrous, parenchyma)

Question 11

why are routine complete blood counts taken?

Answer 11

1. asses for any systemic involvement of disease process

2. determine if any contraindications to therapies

Question 12

what tests are done to yield systemic inflammation

Answer 12

ERS, C reactive protein, other acute phase proteins: hemoglobin, albumin

Question 13

what tests are done to help classify systemic polyarticular inflammatory arthritis

Answer 13

Rh factor and antinuclear antibodies

Question 14

why are joint

Answer 14

fluid should be obtained and analyzed when there is a monoarthritis, undiagnosed polyarthritis, or joint swelling out of proportion to others

Question 15

why check for in joints?

Answer 15

does it hurt when touched

swelling

Question 16

what can joint fluid aspiration be diagnostic for?

Answer 16

crystal induced arthritis and septic arthritis

Question 17

what can X-rays be useful for?

Answer 17

ankylosing spondylitis
calcium pryophosphate deposition disease
osteoarthritis
RA: serial X-rays helpful with progress of disease

Question 18

S T L

Answer 18

swelling 0(none)- 4(distended capsule)
tenderness 0(no pain)-4( won't let touch)
limitations 0(no limitations)-4(totally ankylosed)

Question 19

initial concerns for musculoskeletal complains

Answer 19

articular or non
acute or chronic
inflammatory or non
pauci or polyarticular

Question 20

DMARD’s

Answer 20

disease modifying anti-rheumatic drugs

• hydrocychloroquin, gold, methotrexate, etc.
• used to treat underlying immune defects of many autoimmune disease

Question 21

treatment of arthritis

Answer 21

exercise
physical therapy
NSAID's (manage symptoms)
occupational therapies 
corticosteroids
DMARD's